Iktos Engine
APIs for agentic workflows and computational chemistry pipelines
Company profile
Company profile
Iktos is a pioneering AI and robotics company transforming drug discovery through fully integrated automation. Founded in 2016 and headquartered in Paris, France, Iktos has developed a comprehensive platform that combines generative AI, retrosynthesis planning, and robotic automation to accelerate the drug discovery process. The company's flagship product, Makya, is a generative AI SaaS platform designed by chemists for chemists that creates diverse, novel, and synthetically accessible molecules optimized for drug development. Spaya, their AI-driven retrosynthesis platform, rapidly identifies feasible synthetic routes by converting target compounds into commercially available starting materials in seconds. Iktos Robotics completes the ecosystem by managing the entire synthetic process through automated workflows, from ordering raw materials to executing chemical synthesis, purification, analysis, and biological testing. The platform enables a fully digitized, AI-driven Design-Make-Test-Analyze (DMTA) cycle that significantly reduces drug discovery timelines to under 24 months. Iktos serves pharmaceutical companies, biotech firms, and academic institutions, having completed over 60 collaborations since inception. The company maintains an in-house pipeline targeting areas including inflammation, auto-immune diseases, obesity, metabolism, and immuno-oncology. Iktos has been recognized with a prestigious European Innovation Council (EIC) Accelerator grant for its groundbreaking work integrating generative AI, robotics, and high-precision biological screening.
Company description Iktos official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Api Only · Cloud Saas · On Premise deployment with recorded integration context.
Recorded integration context: 35+ chemical building block providers, Chemspeed robotics platform, Jupyter Notebook, Knime, Pipeline Pilot, Reaxys (Elsevier partnership).
Company milestones
Makya 2.0 launch with new data analysis and visualization experience (2026); Partnership with Chemspeed announced (March 2026); Pierre Fabre Laboratories collaboration announced (January 2026); Iktos Engine APIs for Agentic workflows launched (May 2026); New ligand-based design models released (January 2026)
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
APIs for agentic workflows and computational chemistry pipelines
High-throughput phenotypic screening platform for biological validation
Fully automated synthesis and analysis platform for AI-driven drug discovery
Orchestration AI for managing automated drug discovery workflows
Generative AI platform for de novo drug design, designed by chemists for chemists
AI-driven retrosynthesis platform that transforms target compounds into commercially available starting materials in seconds
High-throughput API for scoring synthetic feasibility of molecules at scale
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
ACS omega · Jul 28, 2026
RNA-binding protein diversity and NLS arginines regulate FUS mixing in mRNA-rich compartments.Cell reports · Jun 23, 2026
Peptide cheminformatics tools: making computational tasks accessible in peptide drug discovery.Drug discovery today · Mar 1, 2026
Thinking outside the library: cluster synthesis of diverse molecules on a single robotic platform.Chemical science · Feb 11, 2026
Large scale compound selection guided by cell painting reveals activity cliffs and functional relationships.Communications biology · Jan 13, 2026
Growing and linking optimizers: synthesis-driven molecule design.Briefings in bioinformatics · Aug 31, 2025
Clinical validation
No linked records are currently available.
Regulatory
No linked records are currently available.
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
with same number of chemists through automation
drug discovery timeline reduction
parallel synthesis capacity via Chemspeed platform
retrosynthesis route identification in seconds
exploration capability of generative AI
Partnership to unlock new possibilities in automated chemical research for pharmaceutical companies
Integrated drug discovery collaboration using Iktos's AI and robotics platform
Strategic partnership combining Reaxys chemistry database with Iktos's AI for predictive retrosynthesis and synthetic accessibility tools
05 · Leadership
Leadership profiles and professional links from the current Company record.
06 · Company updates
Recent articles published on Iktos's official website.
No Company updates are currently listed.
07 · HAIC coverage
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08 · Official presence
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09 · Market pathway
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Market context
Companies using AI, machine learning, or computational biology to discover new drug candidates, identify drug targets, predict drug efficacy, or accelerate pharmaceutical development. Includes both small molecule and biologics development, precision oncology drug discovery, and AI-driven target identification and molecule design.
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