Thinking outside the library: cluster synthesis of diverse molecules on a single robotic platform.

Franck Le Vaillant¹, Luidgi Gromat², Clémentine Pescheteau¹, Nicolas Ducrot², Aurélien Demilly², Jean-Christophe Meillon¹, Nicolas Do Huu², Quentin Perron²

¹Iktos Robotics Laboratory 25-27 Avenue du Québec 91140 Villebon-sur-Yvette France franck.levaillant@iktos.com.

²Iktos 65 rue de Prony 75017 Paris France.

PubMed PMC DOI PDF

Abstract

The development of a general autonomous platform for organic synthesis that enables faster, flexible and efficient delivery of target molecules is an attractive strategy for many fields such as drug discovery and materials science. Traditionally, automated parallel synthesis relies on the synthesis of libraries of various sizes, sharing the same transformations and name reactions with defined reac…

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