Company profile

Activ Surgical

Intraoperative Intelligence Brings Infinite Possibilities

Surgical AI & RoboticsSeries B stage

Company profile

About Activ Surgical

Activ Surgical is a surgical intelligence company that has developed the only commercially available dye-free perfusion imaging technology for the operating room. Using patented laser speckle contrast imaging (LSCI), Activ reveals blood flow, tissue perfusion, and critical structures directly from tissue in real time, without requiring injected dyes like ICG fluorescence. The technology is physics-based, quantitative, and repeatable, providing surgeons with continuous perfusion assessment throughout procedures rather than time-limited snapshots. The company's ActivSight Intelligent Light system is FDA-cleared and CE-marked, and has been used in over 2,000 surgical cases across 17+ countries. Activ's technology integrates into multiple surgical platforms including robotic surgery systems, laparoscopic equipment, microscopy/exoscopy platforms, and open surgery settings. The company serves both surgeons directly and partners with surgical platform manufacturers and OEMs to integrate intelligence capabilities into their systems. Activ Surgical's approach addresses a critical limitation in surgery: surgeons make life-critical decisions based on what they can see, but blood flow and tissue viability beneath the surface remain invisible until complications occur. By providing continuous, on-demand perfusion intelligence, the technology enables surgeons to adjust surgical plans in real time—occurring in approximately 20% of cases where the technology is used. Clinical evidence demonstrates significant outcomes including reduced anastomotic leak rates in colorectal surgery and decreased unnecessary tissue removal.

Company description Activ Surgical official website

Mission. Our mission is for every surgical imaging system to deliver intelligent information that reduces surgical complication rates, ushering in a new standard of patient care and safety.

Primary marketSurgical AI & Robotics
Commercial modelCommercial information available on request
Company presenceLinkedIn X
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Bariatric surgery
  • Cholecystectomy
  • Colorectal surgery
  • Esophagectomy
  • Thoracic/Foregut surgery

Who it serves

  • Health Systems
  • Hospitals
  • Surgical Centers

Deployment & integration

Embedded deployment with recorded integration context.

Recorded integration context: Compatible with existing laparoscopic systems, Compatible with existing robotic surgical systems.

Geographic context

MarketsCE Mark regions · European Union · United States
Company sourceOfficial website

Company milestones

Platform expansion

CE Mark approval December 2022, first international procedure completed, over 200 patient procedures, FDA 510(k) clearance in 2021, multiple pilot hospital sites established

Partnerships

Recorded partners

  • Children's National Medical Center
  • Maastricht University Medical Center (MUMC+)
  • Multiple major hospital networks across U.S. and Europe as pilot sites
  • Northwell Health
  • University of Cologne

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

ActivEdge Platform

AI/AR/ML platform powering surgical innovation and intelligent visualization

Platform · EmbeddedCompany source

ActivSight Intelligent Light

First modular multimodal advanced visualization system for minimally invasive surgery

Device · EmbeddedCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

Colorectal surgery leak rates up to 15%

$30,000+ cost per leak, 12 days additional length of stay

Bariatric surgery leak rates up to 8%

$66,000 per leak, 15 days additional length of stay

Esophagectomy leak rates of 20%

12-25% readmission rate, 7-73 days additional length of stay

400,000+ deaths annually due to avoidable complications in U.S.

26% of all medical errors are preventable surgical errors

$36B+ global cost for preventable medical errors

Preventable medical errors are 3rd leading cause of death

Maastricht University Medical Center (MUMC+)

Advanced visualization during surgery to reduce surgical complications

Seamless integration enabling advanced visualization capabilities

Multiple major hospital networks (US and Europe)

Pilot implementation of ActivSight for clinical validation

Over 200 patients treated successfully across multiple IRB studies

University of Cologne

Enhanced surgical vision to reduce unintended medical errors

Improved surgical outcomes through enhanced visualization

Northwell Health

Real-time blood supply visualization for surgical decision-making

Reproducible real-time blood supply assessment enabling reliable surgical decisions

Ospedale Maggiore Policlinico di Milano

Integration of laparoscopic perfusion technology for surgical procedures

UNLV School of Medicine

Anastomotic leak prevention in colorectal surgery using continuous perfusion assessment

2.5% leak rate vs. 5-15% traditional rate; 17.5% of cases resulted in surgical plan adjustments with 0% leaks in that cohort; 11.7% decreased tissue removal by 3.6 cm

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

Nancy Pervere

Regional Vice President of Operations

LinkedIn

06 · Company updates

Updates from Activ Surgical

Recent articles published on Activ Surgical's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Surgical AI & Robotics

Companies developing surgical technologies enhanced by AI, including robotic surgical systems, AI-powered surgical assistance and navigation tools, autonomous surgical robotics, and surgical data and analytics platforms. Covers both the performance of surgery and the analysis of surgical outcomes and OR efficiency.

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10 · Pro research

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Expanded Company research is in development.

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Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

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