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Peer-Reviewed Publication
Dis Colon Rectum2024;67(6):850-859.June 1, 2024Journal Article

Clinical Utility of Laser Speckle Contrast Imaging and Real-Time Quantification of Bowel Perfusion in Minimally Invasive Left-Sided Colorectal Resections.

Garrett C Skinner1,2, Yao Z Liu2,3, Alan E Harzman4, Syed G Husain4, Alessandra C Gasior4, Lisa A Cunningham4, Amber L Traugott4, Christopher J McCulloh2, Matthew F Kalady4, Peter C Kim2,3, Emily S Huang4
1Department of Surgery, Jacobs School of Medicine and Biochemical Sciences, University at Buffalo, Buffalo, New York.
2Activ Surgical, Boston, Massachusetts.
3Department of Surgery, The Warren Alpert Medical School, Brown University, Providence, Rhode Island.
4Division of Colorectal Surgery, Department of Surgery, The Ohio State University Wexner Medical Center and James Comprehensive Cancer Center, Columbus, Ohio.

Abstract

BACKGROUND: Left-sided colorectal surgery demonstrates high anastomotic leak rates, with tissue ischemia thought to influence outcomes. Indocyanine green is commonly used for perfusion assessment, but evidence remains mixed for whether it reduces colorectal anastomotic leaks. Laser speckle contrast imaging provides dye-free perfusion assessment in real-time through perfusion heat maps and quantifi…

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