X-Automate
High-throughput automation and physical AI robotics for wet-lab experiments
Company profile
AI-powered drug discovery and development platform transforming how medicines are created
Company profile
Xaira Therapeutics is fundamentally transforming how medicines are discovered and developed by operating at the intersection of AI and drug development. The company has built a full-stack, AI-powered therapeutics engine called X-Suite that bridges digital and physical worlds. Their platform includes X-Cell for decoding disease biology using the largest single-cell genomic perturbation dataset ever generated, X-Design for computationally designing therapeutic molecules based on Nobel Prize-winning foundations, X-Patient for identifying responder populations, X-Scientist as an agentic AI research platform, and X-Automate for high-throughput lab automation. Unlike traditional biopharma approaches that rely on statistical correlations, Xaira directly measures biological system responses to perturbations at massive scale to learn actual causal disease mechanisms. The company unifies computational data analysis with physical lab experimentation under one roof, creating a virtuous cycle where every experimental result sharpens underlying AI models. Their emerging pipeline focuses on AI-derived biologic medicines, particularly antibody and protein therapeutics, addressing complex diseases. Xaira's mission is to develop 10x more medicines to help 10x more patients over the next 10 years, with particular focus on complex and historically underserved disease populations. The company's approach has already demonstrated success in rapidly creating drug-like antibody leads and drugging previously undruggable targets.
Company description Xaira Therapeutics official website
Mission. We are fundamentally transforming how we discover and develop medicines—end to end. Purpose-built from inception to operate at the intersection of AI and drug development, we are united in our mission to decode disease, design therapies, and deliver cures.
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
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On Premise · Other deployment with recorded integration context.
Company milestones
June 2025: Unveiled X-Atlas/Orion, largest publicly available Perturb-seq atlas. March 2026: Launched X-Cell virtual cell model achieving state-of-the-art performance. July 2026: Unveiled pipeline of AI-derived therapeutics and announced key leadership appointments (Dr. Ian McCaffery as SVP Translational Science, Dr. Ci Chu promoted to Chief Discovery Officer, Dr. Bo Wang to Chief AI Scientist). September 2026: Won Fierce AI Innovation Award for Preclinical Development. October 2026: Revealed antibody platform and first pipeline programs.
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
High-throughput automation and physical AI robotics for wet-lab experiments
AI model that decodes cellular pathways to reveal novel disease targets and mechanisms
Generative AI that designs entirely new, highly developable therapeutic molecules
AI model that identifies patient responder populations at a molecular level
AI-derived therapeutic programs spanning multiple modalities and indications
Agentic AI system that functions as a virtual drug hunter to accelerate discovery
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Signal transduction and targeted therapy · Jul 16, 2026
Region-Level Design and Analysis of CRISPR Perturbation Screens with FRACTEL.bioRxiv : the preprint server for biology · Jul 7, 2026
Interorganelle competition for linoleic acid underlies steatotic liver pathology.bioRxiv : the preprint server for biology · Jan 11, 2026
The immunogenicity database collaborative: a standardized, publicly available database for clinical immunogenicity observations and insights.Frontiers in immunology · Jan 1, 2026
A pooled Cell Painting CRISPR screening platform enables de novo inference of gene function by self-supervised deep learning.Nature communications · Dec 16, 2025
Engineered ipilimumab variants that bind human and mouse CTLA-4.mAbs · Dec 1, 2025
Clinical validation
No linked records are currently available.
Regulatory
No linked records are currently available.
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
by leveraging AI to accelerate discovery and development
by expanding ability to treat complex and underserved populations
for XA-1 program with 18 confirmed binders from 182 designed sequences
best binder for XA-1 human target
for XA-1 program from start to progressable binder
De novo design of progressable antibodies for precision oncology target requiring epitope selectivity and cross-reactivity
7 weeks from start to lead molecule with 10% binder rate, 17 nM affinity to human target
05 · Leadership
Leadership profiles and professional links from the current Company record.
No active leadership profiles are currently listed.
06 · Company updates
Recent articles published on Xaira Therapeutics's official website.
07 · HAIC coverage
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08 · Official presence
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09 · Market pathway
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Market context
Companies using AI, machine learning, or computational biology to discover new drug candidates, identify drug targets, predict drug efficacy, or accelerate pharmaceutical development. Includes both small molecule and biologics development, precision oncology drug discovery, and AI-driven target identification and molecule design.
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