Company profile

Lantern Pharma

Drug Discovery & Development

Company profile

About Lantern Pharma

Lantern Pharma Inc. is a publicly-traded, clinical-stage biopharmaceutical company focused on transforming oncology drug development through artificial intelligence and precision medicine. The company operates at the intersection of AI, genomics, and machine learning to deliver targeted cancer therapies to the right patients with significantly reduced development costs and timelines. At the core of Lantern's approach is RADR® (Response Algorithm for Drug Positioning & Rescue), a proprietary AI-powered platform that analyzes over 200 billion oncology-specific data points using more than 200 advanced machine learning algorithms. The platform integrates transcriptome data, genomic data, and drug sensitivity information to predict patient responses, identify biomarkers, and stratify patient populations for clinical trials. This data-driven approach enables the company to rescue and revitalize promising oncology compounds while personalizing cancer treatments. Lantern's current portfolio includes three lead drug candidates and an ADC program spanning 12 cancer indications. The company has one lead product candidate (LP-300) in Phase 2 clinical testing through the Harmonic™ trial for never-smoker patients with non-small cell lung cancer, and Phase 1 programs for LP-184 (advanced solid tumors and glioblastoma) and LP-284 (non-Hodgkin's lymphoma). The company has also developed withZeta.ai, an AI research module that unifies clinical, molecular, and therapeutic information for rare and understudied cancers. Lantern Pharma manages an innovative patent portfolio with 95 issued patents and pending applications across 14 patent families.

Company description Lantern Pharma official website

Primary marketDrug Discovery & Development
Commercial modelCommercial information available on request
Company presenceOfficial website
Work at Lantern Pharma?

Claim this profile to manage Company information and connect with the Health AI Central audience.

Claim this listing

01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Advanced solid tumors
  • DNA damage repair deficient cancers
  • Glioblastoma (GBM)
  • Non-Hodgkin's lymphoma
  • Non-small cell lung cancer (NSCLC) adenocarcinoma
  • Pancreatic cancer
  • Triple-negative breast cancer (TNBC)

Who it serves

  • Clinical trial sites
  • Pharma
  • Research institutions

Deployment & integration

Cloud Saas · Other deployment with recorded integration context.

Geographic context

MarketsUnited States
Company sourceOfficial website

Company milestones

Platform expansion

FDA authorization for Harmonic™ Phase 2 trial. August 2024: Announced preliminary patient data showing 86% clinical benefit rate. June 2026 (future date in content): Reported HARMONIC™ data on progression-free survival. Phase 1a enrollment completed for LP-184. Launched withZeta.ai AI research module. RADR® platform exceeded 200 billion data points.

Partnerships

Recorded partners

No partners are currently listed.

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

LP-184

Novel synthetically lethal molecule targeting DNA damage repair deficient cancers

Other · OtherCompany source

LP-284

Novel synthetically lethal molecule for relapsed or refractory non-Hodgkin's lymphoma

Other · OtherCompany source

LP-300

Investigational drug for never smokers with non-small cell lung cancer

Other · OtherCompany source

PredictBBB.ai

AI platform for blood-brain barrier penetration prediction

Platform · OtherCompany source

RADR® (Response Algorithm for Drug Positioning & Rescue)

AI-powered platform for oncology drug development and patient response prediction

Platform · OtherCompany source

withZeta.ai

AI Co-Scientist for rare cancer drug discovery and development

Platform · Cloud SaaSCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

Quantitative characterization of platelet count and alanine aminotransferase dynamics to inform personalized dosing in the first-in-human LP-184 trial.

Cancer chemotherapy and pharmacology · Aug 12, 2026

A first-in-human phase 1a study of LP-184, a tumor-site activated novel alkylating agent, in patients with advanced solid tumors.

Investigational new drugs · Jul 7, 2026

Chemotherapeutic induction of cytosolic single-stranded DNA accumulation sensitizes triple-negative breast cancer to immunotherapy.

Journal for immunotherapy of cancer · Jun 29, 2026

Phase II Trial of LP-300 in Combination With Carboplatin and Pemetrexed in Never Smoker Patients With Relapsed Advanced Primary Adenocarcinoma of the Lung After Treatment With Tyrosine Kinase Inhibitors.

Clinical lung cancer · Sep 1, 2025

Evaluation of Potency and Specificity of Cryptophycin-Loaded Antibody-Drug Conjugates.

Chembiochem : a European journal of chemical biology · Jan 14, 2025

Clinical outcomes of DNA-damaging agents and DNA damage response inhibitors combinations in cancer: a data-driven review.

Frontiers in oncology · Jan 1, 2025

Clinical validation

Clinical-trial records

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

NCT05456256 · Sponsor · RECRUITING

Study of LP-184 in Patients With Advanced Solid Tumors

NCT05933265 · Sponsor · ACTIVE NOT RECRUITING

Safety, Pharmacokinetics, and Clinical Activity of LP-284 in Adult Patients With Relapsed or Refractory Lymphomas and Solid Tumors

NCT06132503 · Sponsor · RECRUITING

Irofulven in AR-targeted and Docetaxel-Pretreated mCRPC Patients With Drug Response Predictor (DRP®)

NCT03643107 · Sponsor · COMPLETED

Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

NCT00039780 · Sponsor · COMPLETED

Phase 3 Study of Tavocept Versus Placebo in Patients With Newly Diagnosed or Relapsed Advanced Primary Adenocarcinoma of the Lung Treated With Docetaxel or Paclitaxel Plus Cisplatin

NCT00966914 · Sponsor · COMPLETED

Regulatory

Regulatory records

No linked records are currently available.

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

86% clinical benefit rate

Initial patient cohort in Harmonic™ Phase 2 trial for LP-300

12x higher success rate

Biomarker-based trials compared to non-biomarker trials

Progression-free survival benefit

LP-300 in EGFR Exon 21 L858R lung cancer, deepens with treatment duration

HARMONIC™ Phase 2 Trial - Initial Patient Cohort

Treatment of never smokers with relapsed advanced primary adenocarcinoma of the lung (NSCLC) using LP-300 combination therapy

86% clinical benefit rate in initial patient cohort

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

06 · Company updates

Updates from Lantern Pharma

Recent articles published on Lantern Pharma's official website.

No Company updates are currently listed.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Drug Discovery & Development

Companies using AI, machine learning, or computational biology to discover new drug candidates, identify drug targets, predict drug efficacy, or accelerate pharmaceutical development. Includes both small molecule and biologics development, precision oncology drug discovery, and AI-driven target identification and molecule design.

Explore the full market directory or compare this Company with additional active profiles.

View all Companies in this market

10 · Pro research

Coming soon

Expanded Company research is in development.

Health AI Central Pro · Coming Soon

Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

Coming Soon