Company profile

Inflammatix

Pathology & Laboratory Diagnostics

Company profile

About Inflammatix

Inflammatix is a molecular diagnostics company that has developed a first-in-class approach to diagnosing acute infections and sepsis by 'reading' the immune system's response rather than targeting pathogens directly. The company's flagship product, TriVerity, is an FDA-cleared diagnostic test designed for emergency department use that provides three actionable scores: likelihood of bacterial infection, likelihood of viral infection, and all-cause illness severity (defined as risk of progression to mechanical ventilation, vasopressors, or renal replacement therapy within seven days). The company's technology is powered by measuring mRNA profiles from immune cells in whole blood, combined with machine learning and artificial intelligence to interpret these host response signatures. This approach addresses a critical limitation of traditional pathogen-targeting tests, which are often insensitive because most infections remain locally contained and don't penetrate the bloodstream. Inflammatix's immune cells circulate into the blood after fighting infections locally, allowing their signatures to be measured and analyzed. Inflammatix leverages expertise in bioinformatics, molecular biology, and machine learning to develop diagnostics that help physicians make confident and timely clinical decisions in emergency settings where time, space, and certainty are in short supply. The company's mission centers on empowering emergency clinicians to rapidly recognize and act early on acute infections with unparalleled precision, transforming triage through early actionability, prognostic clarity, and exceptional accuracy that has been clinically proven to exceed standard of care.

Company description Inflammatix official website

Primary marketPathology & Laboratory Diagnostics
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Acute infections
  • Bacterial infections
  • Sepsis
  • Viral infections

Who it serves

  • Emergency Clinicians
  • Emergency Departments
  • Hospitals

Deployment & integration

Other deployment with recorded integration context.

Geographic context

MarketsNot currently listed
Company sourceOfficial website

Company milestones

Platform expansion

FDA clearance received for first-in-class TriVerity Test

Partnerships

Recorded partners

No partners are currently listed.

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

BacVerity

Pipeline diagnostic for bacterial infections

Device · OtherCompany source

RespVerity

Pipeline diagnostic for respiratory infections

Device · OtherCompany source

TriVerity

First-in-class rapid diagnostic test for acute infections and sepsis using host response mRNA

Device · OtherCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

Real-world clinical evaluation of the Inflammatix TriVerity test for sepsis at the emergency department: an Acutelines study.

Internal and emergency medicine · Jul 8, 2026

Quantifying immune dysregulation in pneumonia and sepsis with a parsimonious machine-learning model: a multicohort analysis across care settings and reanalysis of a hydrocortisone randomised controlled trial.

The Lancet. Respiratory medicine · Apr 1, 2026

Endotype trajectories: better understanding for better sepsis management.

Intensive care medicine · Mar 1, 2026

Endothelial glycocalyx degradation and its association with clinical outcomes and host response aberrations in community-acquired pneumonia across different care settings.

Critical care (London, England) · Jan 27, 2026

A consensus immune dysregulation framework for sepsis and critical illnesses.

Nature medicine · Dec 1, 2025

IMX-SEV-3b mRNA classifier predicts ICU care and 30-day mortality in febrile neutropenic emergency department patients.

The American journal of emergency medicine · Dec 1, 2025

Clinical validation

Clinical-trial records

MASTERMIND-Pneumonia Study (Also Known as Pneumonia Direct Pilot)

NCT06181669 · Mentioned · COMPLETED

TriVerity™ for Improved Management of Emergency Department (ED) Patients With Suspected Infections

NCT06637904 · Sponsor · RECRUITING

TriVerity in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis

NCT04094818 · Sponsor · COMPLETED

Sepsis Prognosis and Diagnosis in the Emergency Department (SPEED)

NCT05639504 · Sponsor · WITHDRAWN

Clinical Validation of HostDx Sepsis™ on NanoString; a Prospective Observational Validation Trial

NCT04414189 · Sponsor · COMPLETED

HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections: a Multicenter Pilot Study

NCT03744741 · Sponsor · COMPLETED

Regulatory

Regulatory records

TriVerity

K241676 · 510k · Jan 10, 2025

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

Early actionability in emergency department triage

Precision decision-making when time, space, and certainty are in short supply

Prognostic clarity for illness severity

Risk of progression to mechanical ventilation, vasopressors, and/or renal replacement therapy within seven days

Exceptional accuracy

Clinically proven to be better than the standard of care

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

06 · Company updates

Updates from Inflammatix

Recent articles published on Inflammatix's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Pathology & Laboratory Diagnostics

Companies applying AI to digital pathology, histopathology slide analysis, laboratory diagnostics, or biomarker discovery. Includes AI-powered interpretation of lab test results, at-home diagnostic devices with AI analysis, and platforms that analyze tissue samples or biological specimens to support clinical diagnosis.

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10 · Pro research

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Expanded Company research is in development.

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Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

Coming Soon