Company profile

Combinostics

Medical Imaging & Radiology

Company profile

About Combinostics

Combinostics is a medical imaging AI company specializing in neurological disorders, offering the only complete AI solution for entire patient care pathways of major neurodegenerative diseases. Founded by experts with over 20 years of neuroimaging experience, the company developed the cNeuro platform, which integrates multiple applications to support clinicians from early detection through disease management. The cNeuro platform consists of cMRI for fully automated brain MRI quantification, cDSI for AI-supported differential diagnosis and disease progression prediction, cPET for amyloid and FDG brain PET quantification, and cDAT for automated quantification of DAT SPECT images. The platform combines imaging biomarkers with clinical data, neuropsychological tests, and demographic information to provide comprehensive patient insights. Combinostics serves radiologists, neurologists, and memory clinics across health systems, enabling better collaboration between disciplines. The company's solutions support diagnosis of Alzheimer's disease, frontotemporal dementia, vascular dementia, dementia with Lewy bodies, and multiple sclerosis. With validated imaging biomarkers and machine learning methods trained on data from over 2,000 patients with confirmed neurodegenerative diseases, cNeuro provides quantitative, objective information that helps clinicians make earlier, more confident diagnoses and data-driven decisions about additional testing. The company maintains strong partnerships with leading Nordic institutions and the international clinical community.

Company description Combinostics official website

Primary marketMedical Imaging & Radiology
Commercial modelCommercial information available on request
Company presenceLinkedIn X
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Alzheimer's disease
  • Cognitive impairment
  • Dementia with Lewy bodies
  • Frontotemporal dementia
  • Multiple sclerosis
  • Neurodegenerative diseases
  • Vascular dementia

Who it serves

  • Health Systems
  • Hospitals
  • Memory Clinics
  • Radiology Centers
  • Research Institutions

Deployment & integration

Cloud Saas deployment with recorded integration context.

Geographic context

MarketsEurope · Finland · Sweden · Switzerland · United States
Company sourceOfficial website

Company milestones

Platform expansion

Acquisition agreement with SyntheticMR announced November 2024; cDAT application for DAT SPECT quantification released in Europe December 2023; cPET application received FDA 510(k) clearance September 2023; cPET application released in Europe July 2023; Participation in PROMINENT Project for precision medicine in neurodegenerative diseases June 2023

Partnerships

Recorded partners

  • Chesapeake Medical Imaging
  • CIMF Fribourg Switzerland
  • Karolinska Institute
  • Karolinska University Hospital
  • PROMINENT Project consortium
  • SyntheticMR (acquisition agreement announced November 2024)
  • Unilabs Sweden

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

cNeuro cDAT

Automated quantification of DAT SPECT images for neurological disorders

Software · Cloud SaaSCompany source

cNeuro cDSI

AI-supported differential diagnosis and prediction of neurodegenerative diseases

Platform · Cloud SaaSCompany source

cNeuro cMRI

Fully automated brain MRI quantification for radiologists

Software · Cloud SaaSCompany source

cNeuro cPET

Automated quantification of amyloid and FDG brain PET imaging

Software · Cloud SaaSCompany source

Dementia Differential Analysis Report

MRI-based differential diagnosis report for neurodegenerative diseases

Software · Cloud SaaSCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

Earlier diagnosis

Enables more confident, earlier diagnosis of neurodegenerative diseases

Improved differential diagnosis

Quantified information helps with differential diagnosis in memory clinics

Data-driven testing decisions

Helps clinicians make evidence-based decisions about whether additional testing is necessary

Chesapeake Medical Imaging

Using cMRI for more objective data and integrations in software-driven imaging quantification in neuroradiology

Benefits seen from tools such as cMRI for objective data in neuroradiology workflows

CIMF Fribourg, Switzerland

Daily use for all dementia investigations and some MS patients, particularly useful in intermediate situations with doubt about existence or type of atrophy and for assessing follow-up scans

cNeuro usage and reporting are highly appreciated by referring physicians

Karolinska University Hospital Memory Clinic

Using cNeuro for differential diagnosis and assessing whether cognitive issues are due to dementia in memory clinic patients

cNeuro has become an indispensable tool for the memory clinic, with quantified information helping with differential diagnosis

Unilabs Sweden

Getting quantitative information when reading scans and sharing imaging information with referring organizations to enable combination of imaging data with clinical data in cNeuro cDSI

Enables sharing of imaging information with referring organizations for comprehensive patient data analysis

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

Lennart Thurfjell

Chief Operating Officer (COO) and Co-Founder

LinkedIn

Jyrki Lötjönen

Chief Scientific Officer (CSO) and Co-Founder

LinkedIn

Jussi Mattila

Chief Technology Officer (CTO) and Co-Founder

LinkedIn

Mikael Dahlke

Head of Quality Assurance

LinkedIn

Elena Bonke

Medical Science Liaison, Clinical App Specialist

Juha Koikkalainen

Senior Imaging Scientist

Antti Tolonen

Senior Imaging Scientist

Markus Niiranen

Lead Software Developer / Team Manager

06 · Company updates

Updates from Combinostics

Recent articles published on Combinostics's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Medical Imaging & Radiology

Companies that apply AI to analyze medical images for diagnostic purposes, workflow optimization, or clinical decision support. Covers general radiology (X-rays, CT scans, MRIs, ultrasounds) across multiple organ systems, as well as specialized imaging in ophthalmology and dermatology.

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10 · Pro research

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Expanded Company research is in development.

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Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

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