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Peer-Reviewed Publication
J Obstet Gynaecol2026;46(1):2709737.December 1, 2026Journal Article

Pregnancy biomarkers as early indicators of cardiovascular risk: a discussion article.

Giulia Renda1, Daniele Falco1, Sabina Gallina1, Anna Vittoria Mattioli2
1Department of Neuroscience, Imaging and Clinical Sciences, "G. D'Annunzio" University of Chieti-Pescara, Chieti, Italy.
2Department for Quality of Life Sciences, University of Bologna - Alma Mater Studiorum, Bologna, Italy.

Abstract

Pregnancy provides a unique opportunity for early cardiovascular prevention by revealing maternal vascular and cardiometabolic vulnerability. Placental growth factor (PlGF), uterine artery Doppler and emerging inflammatory biomarkers may improve the identification of placental dysfunction and adverse pregnancy outcomes. However, their ability to predict long-term maternal cardiovascular risk remai…

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