Links between bone fractures and the gut microbiota.

Claes Ohlsson^1,2, Lina Lawenius¹, Louise Grahnemo¹, Klara Sjögren³

¹Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

²Unit of Clinical Pharmacology, Department of Pharmaceuticals, Sahlgrenska University Hospital, Gothenburg, Sweden.

³Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Osteoporosis Centre, Centre for Bone and Arthritis Research at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. klara.sjogren@medic.gu.se.

PubMed DOI

Abstract

As populations age worldwide, the incidence of fractures is increasing, leading to considerable disease burden and increased health-care costs. Bone mineral density (BMD), bone quality and muscle function are major contributors to fracture risk, with muscle function having a critical role in preventing falls. The gut microbiota is well established as a regulator of these parameters in rodents, wit…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Create Free Account Sign In

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.