Peer-Reviewed Publication
Schizophr Res Cogn2026;46100450.September 1, 2026Journal Article
Comparative profiles of anomalous self-experiences and social cognition in clinical high risk for psychosis and autism spectrum disorder.
Kristina Ballestad Gundersen1,2,3, Tina Dam Kristensen2, Alberte C E Jeppesen1,3, Johannes Andresen1,3, Helle Gade Andersen1,2,4, Birgitte Fagerlund3,5, Paolo Fusar-Poli6,7,8, Merete Nordentoft4,9, Bjørn H Ebdrup2,4, Scott W Woods10, Martha E Shenton11,12,13, Barnaby Nelson14,15, , Louise Birkedal Glenthøj1,3
1VIRTU Research Group, Mental Health Center Copenhagen, Copenhagen University Hospital - Bispebjerg and Frederiksberg, Copenhagen, Denmark.
2Center for Neuropsychiatric Schizophrenia Research, Mental Health Centre Glostrup, Copenhagen University Hospital - Amager and Hvidovre, Denmark.
3Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
4Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
5Child and Adolescent Mental Health Center, Copenhagen University Hospital - Bispebjerg Frederiksberg Hospital, Copenhagen, Denmark.
6Department of Brain and Behavioral Sciences, University of Pavia, Italy.
7Early Psychosis: Interventions and Clinical-detection (EPIC) Lab, Department of Psychosis Studies, King's College London, UK.
8Outreach and Support in South-London (OASIS) service, South London and Maudlsey (SLaM) NHS Foundation Trust, UK.
9CORE- Copenhagen Centre for Mental Health Research, Bispebjerg Frederiksberg Hospital, Copenhagen, Denmark.
10Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
11Department of Radiology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
12Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
13Department of Psychiatry, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.
14Orygen, The National Centre of Excellence in Youth Mental Health, Australia.
15Centre for Youth Mental Health, University of Melbourne, Melbourne, VIC, Australia.
Abstract
BACKGROUND: Self-disorders, or anomalous disturbances in the basic sense of self, have been described in psychosis-risk states and may contribute to social cognitive impairment and functioning. This study examined self-disorder severity and associations with social cognition and functioning across individuals at clinical high risk for psychosis (CHR-P), autism spectrum disorder (ASD), and controls…
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