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Health Econ Rev2026June 2, 2026Journal Article

The Spanish transplantation model as a benchmark: clinical, societal, and economic impact of liver transplants in Spain (1984-2024).

Edson Plasencia Sánchez1, Concepción Gómez Gavara2, Glòria Merino Pinto3, Roger Sabater Mezquita3,4, Itxarone Bilbao5,6, Gerardo Blanco-Fernández7,8, Gloria de la Rosa9, Gemma Piella10
1SIMBIOsys Group, Department of Engineering, Universitat Pompeu Fabra, Carrer de Tanger 122, Barcelona, 08018, Spain.
2Department of Hepatic and Biliary Surgery and Transplants, Hospital Universitari Vall d'Hebron, Pg. Vall d'Hebron 119, Barcelona, 08035, Spain. concepcion.gomez@vallhebron.cat.
3Centre de Recerca en Economia i Salut, Departament d'Economia i Empresa, Universitat Pompeu Fabra, Barcelona, 08005, Spain.
4Department of Econometrics, Statistics and Applied Economics, Universitat de Barcelona, Barcelona, 08007, Spain.
5Department of Hepatic and Biliary Surgery and Transplants, Hospital Universitari Vall d'Hebron, Pg. Vall d'Hebron 119, Barcelona, 08035, Spain.
6Department of Surgery, School of Medicine, Universitat Autònoma de Barcelona, Bellaterra, 08193, Spain.
7Sociedad Española de Trasplante Hepático (SETH), Madrid, Spain.
8Servicio de Cirugía Hepatobiliopancreática y Trasplante Hepático, Hospital Universitario de Badajoz, Badajoz, Spain.
9Organización Nacional de Trasplantes (ONT), Ministerio de Sanidad, Madrid, Spain.
10SIMBIOsys Group, Department of Engineering, Universitat Pompeu Fabra, Carrer de Tanger 122, Barcelona, 08018, Spain. gemma.piella@upf.edu.
PubMed DOI

Abstract

Spain leads the world in organ donation, and the 40th anniversary of its first liver transplant was recently commemorated. Our aim was to evaluate the evolution of the Liver Transplantation (LT) program in Spain over its four decades (1984-2024), examining clinical outcomes and societal economic benefits within a mature transplantation framework. Standardized national data from the Organización Na…

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