PhenoScope
Research platform for biomarker discovery and drug development
Company profile
Company profile
SimBioSys is a TechBio company that combines artificial intelligence, spatial biophysics, and data science to individualize cancer therapy and improve patient outcomes. Founded in 2017 by Dr. Joe Peterson, Dr. John Cole, and Tushar Pandey at the University of Illinois, the company emerged from a National Cancer Institute-funded research project focused on novel cancer modeling approaches. SimBioSys has developed a comprehensive platform that addresses tumor heterogeneity by analyzing tumors in their entirety, moving beyond traditional biopsies or 2D pathology slides. Their flagship product, TumorSight Viz, is FDA-cleared for breast cancer surgical planning and transforms DCE-MRI studies into visually detailed, interactive 3D representations that enable precise measurements of tumor volume and distances to anatomical features. The company's technology leverages Convolutional Neural Networks to automatically segment tumors and surrounding tissues, creating digital twins that capture the physical, chemical, and biological characteristics of tumors at tissue and cellular levels. SimBioSys serves breast surgeons, oncologists, and cancer centers with both clinical and research solutions spanning the entire continuum of patient care, from visualization and surgical planning to recurrence risk prediction and treatment response modeling. The company has grown to over 20 employees and maintains research collaborations with leading institutions including Mayo Clinic, UCLA, and the University of Chicago, with backing from premier healthtech venture capital firms and Mayo Clinic as an investor.
Company description SimBioSys official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Cloud Saas deployment with recorded integration context.
Company milestones
FDA clearance for TumorSight Viz. Featured ABC News case study. Growing commercial presence at top cancer centers. Expansion to 20+ employees.
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Research platform for biomarker discovery and drug development
Optimal dosing determination for cancer therapies
Treatment response prediction for personalized cancer therapy
Therapy selection optimization tool
Surgical planning decision support for cancer treatment
Predictive tool for cancer recurrence risk assessment
FDA-cleared 3D visualization tool for breast cancer surgical planning
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Health economics review · Jun 2, 2026
Validation of Clinical Dynamic Contrast-Enhanced Magnetic Resonance Imaging Perfusion Modeling and Neoadjuvant Chemotherapy Response Prediction in Breast Cancer Using 18FDG and 64Cu-DOTA-Trastuzumab Positron Emission Tomography Studies.JCO clinical cancer informatics · Jan 1, 2025
Generative adversarial networks accurately reconstruct pan-cancer histology from pathologic, genomic, and radiographic latent features.Science advances · Nov 15, 2024
Performance of an AI-powered visualization software platform for precision surgery in breast cancer patients.NPJ breast cancer · Nov 14, 2024
Self-consistent signal transduction analysis for modeling context-specific signaling cascades and perturbations.NPJ systems biology and applications · Jul 19, 2024
Pan-Cancer, Genome-Scale Metabolic Network Analysis of over 10,000 Patients Elucidates Relationship between Metabolism and Survival.Cancers · Jun 22, 2024
Clinical validation
No linked records are currently available.
Regulatory
K251766 · 510k · Jul 8, 2025
TumorSight VizK243189 · 510k · Oct 25, 2024
TumorSight VizK231130 · 510k · Dec 26, 2023
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Helped patient avoid mastectomy through precise 3D visualization
Precise calculations from 3D models
Key measurements for surgical planning
Using TumorSight Viz for surgical planning including optimal incision placement and determining need for oncoplastic rearrangements
Improved surgical planning for breast conservation procedures and nipple-areola complex preservation decisions
Used TumorSight Viz AI-powered 3D digital twin to help a 40-year-old breast cancer patient avoid mastectomy and preserve breast tissue
Patient able to avoid mastectomy and preserve breast tissue through more precise surgical planning
Using TumorSight Viz to improve surgeon-patient communication and surgical decision-making for breast cancer treatment
Easier explanation of treatment trajectory and more informed decision-making between surgeon and patient
05 · Leadership
Leadership profiles and professional links from the current Company record.
06 · Company updates
Recent articles published on SimBioSys's official website.
No Company updates are currently listed.
07 · HAIC coverage
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Curated official destinations from the active Company record.
09 · Market pathway
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Market context
Companies using AI to analyze genomic, proteomic, metabolomic, or multi-omics data to provide personalized treatment recommendations, identify genetic risks, or develop targeted therapies. Includes genomic sequencing platforms with AI analysis, preventive medicine based on genetic risk assessment, and longevity care based on molecular and genetic data.
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