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Peer-Reviewed Publication
Nat Cancer2026;7(3):484-493.March 1, 2026Journal Article

Prospective evaluation of artificial intelligence integration into breast cancer screening in multiple workflow settings: the GEMINI study.

Clarisse Florence de Vries1, Gerald Lip2, Roger Todd Staff2, Jaroslaw Artur Dymiter3, Benjamin Tse2, Annie Ng4, Georgia Fox5, Cary Oberije5, Lesley Ann Anderson6,7
1Glasgow Lab for Data Science & AI, Public Health, School of Health and Wellbeing, University of Glasgow, Glasgow, UK. clarisse.devries@glasgow.ac.uk.
2National Health Service Grampian, Aberdeen, UK.
3Grampian Data Safe Haven (DaSH), University of Aberdeen, Aberdeen, UK.
4DeepHealth Inc., Somerville, MA, USA.
5Kheiron Medical Technologies Ltd., London, UK.
6Biostatistics and Health Data Science, Institute of Applied Health Sciences, School of Medicine, Medical Sciences & Nutrition, University of Aberdeen, Aberdeen, UK.
7Interdisciplinary Institute, University of Aberdeen, Aberdeen, UK.

Abstract

Artificial intelligence (AI) tools can improve breast screening performance but different screening sites have varying needs. Here the GEMINI prospective evaluation of 10,889 women, within one UK region, used both live AI integration and simulations to model 17 different ways AI could be used in breast screening. All women received routine care. One AI tool was assessed. When the AI tool recommend…

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