Cohort Study of Initial Diuretic Dosing and Outcomes Among Patients Hospitalized for Congestive Heart Failure: Insights From the Cardiovascular Quality Improvement and Care Innovation Consortium.

Naureen Qadri¹, Erica Kwok¹, Larissa Stanberry¹, Chelsey Thomas², Stephanie J Irausquin³, Divya Gupta⁴, Joseph E Ebinger⁵, Ty J Gluckman⁶, R Kannan Mutharasan⁷, Abhinav Goyal⁴, Nicholas K Brownell⁸, Benjamin M Scirica⁹, P Michael Ho¹⁰, Sandeep R Das^11,12, William Downey³, Steven M Bradley^1,12

¹Minneapolis Heart Institute Foundation Minneapolis MN USA.

²Health Catalyst Minneapolis MN USA.

³Atrium Health Charlotte NC USA.

⁴Department of Medicine, Division of Cardiology Emory University School of Medicine Atlanta GA USA.

⁵Department of Cardiology, Smidt Heart Institute Cedars-Sinai Medical Center Los Angeles CA USA.

⁶Center for Cardiovascular Analytics, Research, and Data Science (CARDS) Providence Heart Institute Portland OR USA.

⁷Division of Cardiology, Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL USA.

⁸Division of Cardiology David Geffen School of Medicine at UCLA Los Angeles CA USA.

⁹Division of Cardiovascular Medicine, Department of Medicine Brigham and Women's Hospital and Harvard Medical School Boston MA USA.

¹⁰Division of Cardiology University of Colorado School of Medicine Aurora CO USA.

¹¹Center for Healthcare Delivery Innovation Allina Health Minneapolis Heart Institute Minneapolis MN USA.

¹²University of Texas Southwestern Medical Center Dallas TX USA.

PubMed PMC DOI PDF

Abstract

BACKGROUND: Little is known about the initial dosing of loop diuretics among patients hospitalized for heart failure and its association with outcomes. METHODS: We identified patients admitted for heart failure at 24 hospitals across two health systems between January 1, 2017, and December 31, 2020. Initial diuretic dose was categorized relative to home dose in furosemide equivalents. The primary…

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Mentioned Companies

Health Catalyst
affiliation

MeSH Terms

Humans0Heart Failure*Female0Male0Aged0Sodium Potassium Chloride Symporter Inhibitors*Patient Readmission0Length of Stay0Acute Kidney Injury0Hospital Mortality0Furosemide*Aged, 80 and over0Retrospective Studies0Treatment Outcome0Hospitalization0Quality Improvement0Dose-Response Relationship, Drug0Middle Aged0United States0

Keywords

diureticsdose–response relationshipheart failurehospitalizationlength of stay

Article Info

PMID: 41757434
PMCID: PMC13055810
DOI: 10.1161/JAHA.124.038783

How to Cite

Qadri N et al. Cohort Study of Initial Diuretic Dosing and Outcomes Among Patients Hospitalized for Congestive Heart Failure: Insights From the Cardiovascular Quality Improvement and Care Innovation Consortium. J Am Heart Assoc2026;15(6):e038783. doi:10.1161/JAHA.124.038783

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