Peer-Reviewed Publication
Eye (Lond)2026;40(5):682-688.April 1, 2026Journal Article
Predicting progression to proliferative diabetic retinopathy using automated versus manual quantification of retinal haemorrhages.
Aditya Verma1,2, Muneeswar G Nittala1, Roxan Mansoori Dara1,3, Marius Facktor4, Chaithanya A Ramachandra4, Malavika Bhaskaranand4, Sandeep Bhat4, Kaushal Solanki4, Chaitra Jayadev5, Swetha B Velaga1, Gavin Robertson6, Bradley Yates7, Rajiv Raman8, SriniVas R Sadda9,10
1Doheny Eye Institute, Pasadena, CA, USA.
2Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA.
3School of Medicine, Meharry Medical College, Nashville, TN, USA.
4Eyenuk Inc, Los Angeles, CA, USA.
5Narayana Nethralaya, Bangalore, India.
6Optos Research and Development, Optos plc, Dunfermline, UK.
7Executive Vice President Product/Solutions Management, (EVP-Product) Optos, Dunfermline, UK.
8Sankara Nethralaya, Chennai, India.
9Doheny Eye Institute, Pasadena, CA, USA. ssadda@doheny.org.
10David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA. ssadda@doheny.org.
Abstract
PURPOSE: To compare automated and manual quantification of retinal haemorrhages in eyes with diabetic retinopathy (DR) and to analyse the risk of progression to proliferative DR (PDR).
METHODS: Retinal haemorrhages on ultra-widefield (UWF) pseudocolor images in eyes with non-proliferative diabetic retinopathy (NPDR) were manually segmented. DR severity was assessed within the seven ETDRS fields a…
Create a free account to keep reading
Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.
Want unlimited research access? See Pro plans