Pulmonary blood volume redistribution in COVID-19 patients of different severity and its predictive value for six-month outcomes in the less pathogenic Omicron variant.

Ge Hu¹, Zhenchen Zhu², Zhengsong Pan^2,3, Weixiong Tan⁴, Wei Han⁵, Zifeng Wu⁴, Zhen Zhou⁴, Xinlun Tian⁶, Wei Song², Yizhou Yu^4,7, Lan Song², Zhengyu Jin²

¹Theranostics and Translational Research Center, National Infrastructures for Translational Medicine, Institute of Clinical Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

²Department of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

³4+4 Medical Doctor Program, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

⁴Deepwise AI Lab, Hangzhou Deepwise & League of PhD Technology Co. Ltd., Hangzhou, China.

⁵Department of Epidemiology and Health Statistics, Institute of Basic Medicine Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

⁶Department of Pulmonary and Critical Care Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

⁷Department of Computer Science, The University of Hong Kong, Hong Kong, China.

PubMed DOI

Abstract

BACKGROUND: The redistribution of pulmonary blood volume (PBV) across COVID-19 severity levels and its prognostic value for the less pathogenic, predominantly upper respiratory tract-infecting Omicron variant remain unclear. This study investigates PBV distribution patterns and validates its predictive utility for Omicron outcomes. METHODS: This retrospective study enrolled consecutive patients (…

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