Incorporating Measures of Cognitive Processing Speed and Brain Volume in Clinical Management of Pediatric Onset Multiple Sclerosis.

Anna Sosa¹, Kimberly A O'Neill¹, Thibo Billiet², Jingyun Chen³, Laura Couvreur², Stijn Denissen⁴, Matthew Lustberg¹, Shayna Pehel¹, Annemie Ribbens², Lauren Krupp⁵

¹Department of Neurology, NYU Langone Medical Center, New York, New York.

²Icometrix, Boston, Massachusetts.

³Icometrix, Boston, Massachusetts; Department of Radiation Oncology, Columbia University Irving Medical Center, New York, New York.

⁴AIMS Lab, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.

⁵Department of Neurology, NYU Langone Medical Center, New York, New York. Electronic address: lauren.krupp@nyulangone.org.

PubMed DOI

Abstract

BACKGROUND: While cognitive processing and brain volume assessments are commonly used in multiple sclerosis (MS) research, they are not routinely incorporated into clinical care. Advances in neuroimaging software now allow for brain volume measurement to be incorporated into standard practice and guide clinical decision-making. METHODS: In this single-center, outpatient, cohort study, pediatric-o…

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