icobrain aria (ARIA Detection)
Detect, measure and grade amyloid-related imaging abnormalities
Company profile
Company profile
Icometrix is a global leader in AI-driven neuroimaging solutions that transform how clinicians diagnose and monitor neurological disorders. The company's flagship icobrain platform uses artificial intelligence to automatically analyze brain MRI scans, detecting and quantifying subtle changes in brain structures and lesions over time. This longitudinal monitoring capability is crucial for timely diagnoses and therapeutic decisions across multiple neurological conditions. Icometrix offers disease-specific solutions for multiple sclerosis, dementia and Alzheimer's disease, amyloid-related imaging abnormalities (ARIA), traumatic brain injury, epilepsy, Parkinson's disease, stroke, and brain tumors. The platform assists radiologists and neurologists by comparing and quantifying brain MRI scans, making complex imaging data more actionable. With 9 FDA-cleared and CE-marked solutions, icometrix is recognized as the #1 validated AI solution for multiple sclerosis. The company's technology has been validated through over 270 scientific publications and is used across 30+ countries by 400+ healthcare institutions, enhancing care for over 7,000 patients. Clinical evidence demonstrates significant improvements in clinical workflows, including 150% increased detection of disease activity in MS, 40% faster radiological reading speed, and 2.5x faster detection of treatment failure. In 2024, GE HealthCare announced its intent to acquire icometrix to strengthen its neurology portfolio with advanced brain MRI assessment solutions. The company is headquartered in Leuven, Belgium, and continues to set the global standard in brain imaging AI through its commitment to precision and personalized medicine in neurology.
Company description Icometrix official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Cloud Saas deployment with recorded integration context.
Company milestones
GE HealthCare announced intent to acquire icometrix in 2024. MSAA and icometrix partnership announced June 2026 to expand MRI Access Program. Participation in RECLAIM observational study across European institutions. CPT-III codes 0865T/0866T now active and processed by over 30 insurers in U.S.
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Detect, measure and grade amyloid-related imaging abnormalities
Supporting differential diagnosis and monitoring of atrophy in dementia
Supporting differential diagnosis of epilepsy through abnormality patterns
Accurately visualize lesion and brain volume changes over time in multiple sclerosis
Quantifies volumes of basal ganglia, brainstem, cerebellum, cortex, and ventricles
Measure stroke lesion volumes and perfusion abnormalities
Quantify traumatic brain injury and track structural changes
Track changes in tumor resection cavity, core, and edema
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Alzheimer's research & therapy · Jun 29, 2026
Spinal cord reserve is associated with multi-dimensional clinical resilience in multiple sclerosis.Journal of neurology · Jun 17, 2026
The relationship between objective and subjective cognitive performance and clinical and MRI disease burden in early multiple sclerosis.Scientific reports · May 16, 2026
The Ischemic Stroke Lesion Segmentation Challenge (ISLES)'24 Dataset: A Multimodal Stroke Imaging Dataset with Hyperacute CT, Acute Postinterventional MRI, and 3-month Clinical Outcomes.Radiology. Artificial intelligence · May 1, 2026
Cross-sectional brain volumetric measures and disability outcomes in relapsing-remitting multiple sclerosis.Journal of neurology · Apr 1, 2026
Incorporating Measures of Cognitive Processing Speed and Brain Volume in Clinical Management of Pediatric Onset Multiple Sclerosis.Pediatric neurology · Feb 1, 2026
Clinical validation
NCT07111637 · Mentioned · RECRUITING
Study to Evaluate the Usability and Value of Integrated Digital Solutions in Medical Care of Participants With Multiple SclerosisNCT05949580 · Sponsor · SUSPENDED
Clinical Impact Through AI-assisted MS Care - A Retrospective Multi-center Observational Study.NCT06280755 · Sponsor · RECRUITING
Clinical Impact Through AI-assisted MS Care - A Prospective Multi-center StudyNCT07032246 · Sponsor · ENROLLING BY INVITATION
Remote MS Care in AntwerpNCT06179758 · Sponsor · ACTIVE NOT RECRUITING
The Impact of Traumatic Brain Injury in the ElderlyNCT04070092 · Mentioned · SUSPENDED
Regulatory
K240712 · 510k · Nov 7, 2024
icobrain-ctpK192962 · 510k · Feb 28, 2020
IcobrainK192130 · 510k · Dec 13, 2019
icobrainK181939 · 510k · Nov 6, 2018
icobrainK161148 · 510k · Aug 9, 2016
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Van Hecke et al., 2021
Van Hecke et al., 2021
Sima et al., 2021
Van Hecke et al., 2021
Clinical evidence
Multiple sclerosis treatment failure detection
2.5x faster detection of treatment failure
Multiple sclerosis disease activity detection and radiological reading efficiency
150% increased detection of disease activity in MS, 35% increase in radiological reading consistency, 40% increase in radiological reading speed
Multiple sclerosis treatment outcomes with icobrain vs drugs alone
68% outcome improvement when employing icobrain vs drugs alone
Multiple sclerosis patient monitoring and detection of subtle changes over time
Improved detection of subtle changes in MS patients that may be missed without icobrain
05 · Leadership
Leadership profiles and professional links from the current Company record.
Joseph Fritz
President of the American Society of Neuroimaging
Tiron Pechet
Assistant Medical Director at Shields Healthcare
06 · Company updates
Recent articles published on Icometrix's official website.
No Company updates are currently listed.
07 · HAIC coverage
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Curated official destinations from the active Company record.
09 · Market pathway
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Companies that apply AI to analyze medical images for diagnostic purposes, workflow optimization, or clinical decision support. Covers general radiology (X-rays, CT scans, MRIs, ultrasounds) across multiple organ systems, as well as specialized imaging in ophthalmology and dermatology.
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Linked research, clinical, and regulatory source pathways.
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