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Peer-Reviewed Publication
Complement Ther Med2025;93103205.October 1, 2025Journal Article

From farm to bedside: Potential of medical cannabis in global health.

Maureen Bilinga Tendwa1, Tejaswini Appidi2, Brylyne Chitsunge3, Michele Moreau4, Blessed Okole5, Lonji Kalombo6, Abba Mallum7, Twalib Ngoma8, Daniel P Weadock9, Eric Tanifum10, Simon Erridge11, Mikael Sodergren12, Rob Sims13, Calvin Johnson14, Ngeh Toyang15, Henry Lowe16, Bashkim Ziberi17, Luc Richner18, Sandra Carrillo19, Stephen Avery20, Judey Pretorius21, Rachel Chikwamba22, Fleury A Nsole Biteghe23, Peter Grinspoon24, Gary Strichtartz25, Sayeda Yasmin-Karim26, Wilfred Ngwa27
1Global Health Catalyst, Boston, USA. Electronic address: BTendwa@ghcuniversity.org.
2John Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address: tappidi1@jhmi.edu.
3Elpasso Farms, Cullinan, South Africa. Electronic address: brylynec@yahoo.com.
4John Hopkins University, School of Medicine, Baltimore, MD, USA. Electronic address: mmoreau1@jh.edu.
5The Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa. Electronic address: bokole@csir.co.za.
6The Council for Scientific and Industrial Research (CSIR), Pretoria, South Africa. Electronic address: lkalombo@csir.co.za.
7Inkosi Albert Luthuli Central Hospital, Durban, South Africa. Electronic address: MalloumA@ukzn.ac.za.
8Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. Electronic address: ngoma_tan@yahoo.com.
9Perelman Center for Advanced Medicine, University of Pennsylvania, USA. Electronic address: docwead1@gmail.com.
10Baylor College of Medicine, Houston, TX, USA. Electronic address: eatanifu@texaschildrens.org.
11Medical Cannabis Research Group, Imperial College, London, United Kingdom. Electronic address: simon.erridge12@imperial.ac.uk.
12Medical Cannabis Research Group, Imperial College, London, United Kingdom. Electronic address: m.sodergren@imperial.ac.uk.
13Primitiv, MI, USA.
14Primitiv, MI, USA. Electronic address: calvin.johnson@gmail.com.
15Flavocure Biotech, USA. Electronic address: ngeh.toyang@edscientific.com.
16Flavocure Biotech, USA. Electronic address: mlowe@mediaone.net.
17University of Tetova, North Macedonia. Electronic address: bashkim.ziberi@unite.edu.mk.
18Vigia AG/Cannavigia, Zurich, Switzerland. Electronic address: press@cannabis-europa.com.
19Faculty of Medicine, University of Panama, Panama. Electronic address: sandra.carillo@uniroma1.it.
20Perelman Center for Advanced Medicine, University of Pennsylvania, USA. Electronic address: Stephen.Avery@pennmedicine.upenn.edu.
21Biomedical Emporium, Pretoria, South Africa. Electronic address: dpretorius@biomedicalemporium.com.
22Advanced Chemistry and Life Sciences division, CSIR South Africa, South Africa. Electronic address: rchikwamba@csir.co.za.
23College of Science, Department of Biotechnology, Northeastern University, Boston, MA, USA. Electronic address: f.nsolebiteghe@northeastern.edu.
24Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: pmgrinspoo@bics.bwh.harvard.edu.
25Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: gstrichz@zeus.bwh.harvard.edu.
26Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: sayeda_yasmin-karim@dfci.harvard.edu.
27John Hopkins University, School of Medicine, Baltimore, MD, USA; Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address: wngwa1@jhmi.edu.

Abstract

INTRODUCTION: The growing opioid crisis and persistent global health disparities underscore the urgent need for alternative therapeutic strategies. Cannabis, with its long-standing historical use and recent legislative developments, presents a potentially significant avenue for addressing these challenges. This review examines the evolving landscape of medicinal cannabis, drawing from historical e…

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