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Peer-Reviewed Publication
J Med Internet Res2025;27e68148.September 11, 2025Journal Article

Real-World Evidence Shows Gaps in Awareness, Medical Help-Seeking, and Diagnosis for Primary Dysmenorrhea but Not Premenstrual Syndrome: Cross-Sectional Observational Study.

Matthias Roos1, Verena Wimmelbacher2, Lisa Klein1, Marija Kesić1, Ann-Katrin Rueß1, Christina Necker2, Nicole Mähler2, Petra Stute3, Christoph Abels2, Tobias Kruse1
1SubjectWell, Denninger Str. 30, Munich, 81679, Germany, +49 89 215 37 4990.
2Bionorica SE, Neumarkt in der Oberpfalz, Germany.
3Department of Obstetrics and Gynecology, University Clinic Inselspital, Bern, Switzerland.
PubMed PMC DOI PDF

Abstract

BACKGROUND: Menstrual complaints are widespread but often stigmatized. The most common is dysmenorrhea, or menstrual cramps, which manifests as mild to severe pain during menstruation and affects >40% of women throughout their reproductive lifespan. Dysmenorrhea is often endured silently or managed through self-medication. Consequently, a vast majority of patients with dysmenorrhea may not be foun…

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