From Simulation to Surgery: Comprehensive Validation of an Optical Sensor for Monitoring Focal Laser Ablation of Solid Organ Tumors.

Rory Geoghegan¹, Songping Sun², Griffith Hughes², Richard Tirado³, Anthony Sisk⁴, Alan Priester⁵, Leonard Marks¹, Shyam Natarajan⁵

¹Department of Urology & the Center for Advanced Surgical & Interventional Technology, University of California Los Angeles, Los Angeles, CA 90095 USA.

²Department of Bioengineering, University of California, Los Angeles.

³Department of Ecology and Evolutionary Biology, University of California, Los Angeles.

⁴Department of Pathology, University of California Los Angeles, USA.

⁵Department of Urology, University of California Los Angeles, USA & Avenda Health (Culver City, CA).

PubMed PMC DOI PDF

Abstract

Solid organ tumors can be treated using focal laser ablation in which a needle housing a laser fiber is inserted into a tumor and oncologic control is achieved through thermally induced tissue coagulation. The key advantage of this procedure over conventional approaches is that it has few side-effects due to its minimally invasive nature. However, the lack of an inexpensive and accurate monitoring…

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