Quantitative Liver Fat Assessment by Handheld Point-of-Care Ultrasound: A Technical Implementation and Pilot Study in Adults.

Dorathy Tamayo-Murillo¹, Jake T Weeks², Cody A Keller², Michael Andre³, Celene Gonzalez², Andrew Li⁴, Eduardo Grunvald⁵, Joy Liau³, Sedighe Hosseini Shabanan², Tanya Wolfson⁶, Jingyi Zuo⁷, Adam Robinson³, Carolina Amador Carrascal⁸, Nevada Sanchez⁸, Scott B Reeder⁹, Aiguo Han⁷, Claude B Sirlin²

¹Department of Radiology, University of California San Diego, La Jolla, CA, USA. Electronic address: dtamayomurillo@health.ucsd.edu.

²Department of Radiology, Liver Imaging Group, University of California San Diego, La Jolla, CA, USA.

³Department of Radiology, University of California San Diego, La Jolla, CA, USA.

⁴Department of Electrical and Computer Engineering, University of Illinois Urbana-Champaign, Urbana, IL, USA.

⁵UCSD Center for Advanced Weight Management, Division of General Internal Medicine, University of California San Diego, La Jolla, CA, USA.

⁶Department of Medicine, Computer And Statistics Laboratory, University of California San Diego, La Jolla, CA, USA.

⁷Department of Biomedical Engineering and Mechanics, Virginia Polytechnic Institute and State University, Blackburg, VA, USA.

⁸Butterfly Network Inc., Burlington, MA, USA.

⁹Departments of Radiology, Medical Physics, Biomedical Engineering, Medicine, and Emergency Medicine, University of Wisconsin, Madison, WI, USA.

PubMed PMC DOI PDF

Abstract

OBJECTIVES: To implement, examine the feasibility of, and evaluate the performance of quantitative ultrasound (QUS) with a handheld point-of-care US (POCUS) device for assessing liver fat in adults. MATERIALS AND METHODS: This prospective IRB-approved, HIPAA-compliant pilot study enrolled adults with overweight or obesity. Participants underwent chemical-shift-encoded magnetic resonance imaging t…

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