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Peer-Reviewed Publication
JACC Adv2024;3(9):101172.September 1, 2024Journal Article

Digital Twin in Managing Hypertension Among People With Type 2 Diabetes: 1-Year Randomized Controlled Trial.

Paramesh Shamanna1, Shashank Joshi2, Mala Dharmalingam3, Arun Vadavi4, Ashok Keshavamurthy5, Lisa Shah6, Shambo Samrat Samajdar7, Jeffrey I Mechanick8
1Department of Diabetes, Bangalore Diabetes Centre, Bangalore, Karnataka, India. Electronic address: drparamesh2@gmail.com.
2Department of Diabetology and Endocrinology, Lilavati Hospital and Research Center, Mumbai, India.
3MS Ramaiah Medical College, Bangalore Endocrinology & Diabetes Research Centre, Bangalore, Karnataka, India.
4Department of Diabetes, Sudha Prevention Centre, Bangalore, Karnataka, India.
5Department of Diabetes, Chandana Clinic, Bangalore, Karnataka, India.
6Twin Health, Mountain View, California.
7Department of Clinical and Experimental Pharmacology, Calcutta School of Tropical Medicine, Kolkata, India.
8The Marie-Josee and Henry R. Kravis Center for Cardiovascular Health at Mount Sinai Fuster Heart Hospital, New York City, New York, USA.

Abstract

BACKGROUND: Digital twin (DT)-guided lifestyle changes induce type 2 diabetes (T2D) remission but effects on hypertension (HTN) in this population are unknown. OBJECTIVES: The purpose of this study was to assess effects of DT vs standard of care (SC) on blood pressure (BP), anti-HTN medication, HTN remission, and microalbuminuria in participants with T2D. METHODS: This is a secondary analysis of…

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