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Peer-Reviewed Publication
J Pathol Inform2024;15100346.December 1, 2024Journal Article

Comparative evaluation of slide scanners, scan settings, and cytopreparations for digital urine cytology.

Jen-Fan Hang1,2, Yen-Chuan Ou3, Wei-Lei Yang4, Tang-Yi Tsao5, Cheng-Hung Yeh4, Chi-Bin Li4, En-Yu Hsu4, Po-Yen Hung4, Yi-Ting Hwang6, Tien-Jen Liu4, Min-Che Tung3
1Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
2School of Medicine and Institution of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
3Division of Urology, Department of Surgery, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan.
4AIxMed, Inc., Santa Clara, CA, United States.
5Department of Pathology, Tung's Taichung MetroHarbor Hospital, Taichung, Taiwan.
6Department of Statistics, National Taipei University, Taipei, Taiwan.

Abstract

BACKGROUND: Acquiring well-focused digital images of cytology slides with scanners can be challenging due to the 3-dimensional nature of the slides. This study evaluates performances of whole-slide images (WSIs) obtained from 2 different cytopreparations by 2 distinct scanners with 3 focus modes. METHODS: Fourteen urine specimens were collected from patients with urothelial carcinoma. Each specim…

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