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Peer-Reviewed Publication
J Am Med Inform Assoc2022;29(9):1471-1479.August 16, 2022Journal Article

Comparing the variability of ingredient, strength, and dose form information from electronic prescriptions with RxNorm drug product descriptions.

Corey A Lester1, Allen J Flynn2, Vincent D Marshall1, Scott Rochowiak3, Brigid Rowell1, James P Bagian4
1Department of Clinical Pharmacy, College of Pharmacy, University of Michigan, Ann Arbor, Michigan, USA.
2Department of Learning Health Sciences, Michigan Medicine, University of Michigan, Ann Arbor, Michigan, USA.
3Surescripts LLC, Minneapolis, Minnesota, USA.
4Center for Risk Analysis Informed Decision Engineering, Department of Industrial and Operations Engineering, College of Engineering, University of Michigan, Ann Arbor, Michigan, USA.

Abstract

OBJECTIVE: To determine the variability of ingredient, strength, and dose form information from drug product descriptions in real-world electronic prescription (e-prescription) data. MATERIALS AND METHODS: A sample of 10 399 324 e-prescriptions from 2019 to 2021 were obtained. Drug product descriptions were analyzed with a named entity extraction model and National Drug Codes (NDCs) were used to…

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