Surescripts

Surescripts

Pharmacy & Medication Management

About Surescripts

Surescripts is the nation's leading health information network company, powering nationwide interoperability through trusted health intelligence sharing. The company connects 2.32 million healthcare professionals and provider organizations across the United States, processing over 30.5 billion network transactions annually. Surescripts enables secure, real-time exchange of clinical and medication data to inform and accelerate care decisions throughout the patient journey. The company's comprehensive product portfolio includes e-prescribing solutions that processed 2.64 billion prescriptions in 2025, Real-Time Prescription Benefit tools that delivered 1 billion responses to prescribers, medication history services providing 3.79 billion records, and electronic prior authorization platforms. Additional offerings include Clinical Direct Messaging for HIPAA-compliant care coordination, Electronic Benefit Verification, formulary management, and the Surescripts Health Information Network for clinical document exchange. Surescripts serves the entire healthcare ecosystem including EHR vendors, health plans, PBMs, pharmacies, health systems, life sciences companies, and specialty care providers. The company's network maintains 99.998% average uptime and has linked 5.97 billion clinical documents. Through its Network Alliance program, Surescripts brings together industry stakeholders to collaborate on solving major healthcare challenges. The company's solutions have demonstrated measurable impact, including 40% lower out-of-pocket costs for high-cost drug classes and improved medication adherence and care coordination nationwide.

Mission & Story

Mission

Inform and accelerate decisions to keep patient care on track

Clinical Focus

Medical conditions and clinical areas addressed by Surescripts.

medication managementchronic disease managementspecialty medicationscontrolled substanceshigh-cost drug therapies

Who It Serves

Health SystemsEHR vendorsHealth PlansPBMsPharmaciesSpecialty PharmaciesLife Sciences CompaniesPatient Access VendorsHealthcare Analytics VendorsLong-term & Post-Acute CarePharmacy Technology Vendors

Milestones & Awards

Recent Milestones

Processed 30.5 billion network transactions in 2025, connected 2.32 million healthcare professionals and organizations, delivered 1 billion Real-Time Prescription Benefit responses, facilitated 104.3 million electronic case reports to public health agencies

Awards & Recognition

White Coat Award program, industry recognition for secure, trusted, high-value network

Key Partnerships

CenterWell PharmacyAccredoSutter HealthNetwork Alliance member organizations

Company Details

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Security & Compliance

HIPAADirect standard

Official Sources

Last updated Jul 1, 2026

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