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Peer-Reviewed Publication
J Diabetes Sci Technol2022;16(2):364-372.March 1, 2022Journal Article

Adjustment of Insulin Pump Settings in Type 1 Diabetes Management: Advisor Pro Device Compared to Physicians' Recommendations.

Revital Nimri1, Tal Oron1, Ido Muller2, Ivana Kraljevic3, Montserrat Martín Alonso4, Paivi Keskinen5, Tanja Milicic6, Asaf Oren7,8, Athanasios Christoforidis9, Marieke den Brinker10, Lutgarda Bozzetto11, Andrea Mario Bolla12, Michal Krcma13, Rosa Anna Rabini14, Shadi Tabba15, Lizl Smith16, Andriani Vazeou17, Giulio Maltoni18, Elisa Giani19, Eran Atlas2, Moshe Phillip1,8
1The Jesse Z and Sara Lea Shafer Institute for Endocrinology and Diabetes, National Center for Childhood Diabetes, Schneider Children's Medical Center of Israel, Petah, Tikva, Israel.
2DreaMed Diabetes Ltd, Petah Tiqva, Israel.
3Department of Endocrinology and Diabetes, UHC Zagreb, School of Medicine, University of Zagreb, Zagreb, Croatia.
4Department of Pediatrics, Children's Endocrinology Unit, University Hospital of Salamanca, Spain.
5Department of Pediatrics, University Hospital of Tampere, Finland.
6Clinic for Endocrinology, Diabetes and Metabolic Diseases, Clinical Center of Serbia, Faculty of Medicine University of Belgrade, Serbia.
7Pediatric Endocrinology and Diabetes Unit, Dana-Dwek Children's Hospital, Tel Aviv Sourasky Medical Center, Israel.
8Sackler School of Medicine, Tel Aviv University, Israel.
9Pediatric Department, Aristotle University of Thessaloniki, Hippokratio General Hospital, Thessaloniki, Greece.
10Department of Pediatrics, Division of Pediatric Endocrinology and Diabetology, Antwerp University Hospital and University of Antwerp, Belgium.
11Department of Clinical Medicine and Surgery, University of Naples "Federico II", Italy.
12Diabetes Research Institute, IRCCS San Raffaele Hospital, Milan, Italy.
13Department of Internal Medicine, Diabetes and Endocrinology Unit, University Hospital Pilsen, Faculty of Medicine in Pilsen, Charles University, Czech Republic.
14Department of Diabetology, Hospital Mazzoni, Ascoli Piceno, Italy.
15Children's Hospital of the King's Daughters, Eastern Virginia Medical School, Norfolk, VA, USA.
16Department of Internal Medicine, Division of Endocrinology, University of Pretoria, South Africa.
17A' Department of Pediatrics, Diabetes Center, P&A Kyriakou, Athens, Greece.
18Department of Pediatrics, University Hospital of Bologna Sant'Orsola-Malpighi Polyclinic, Italy.
19Department of Biomedical Sciences, Humanitas Clinical and Research Center-IRCCS and Humanitas University, Milan, Italy.

Abstract

AIMS: To compare insulin dose adjustments made by physicians to those made by an artificial intelligence-based decision support system, the Advisor Pro, in people with type 1 diabetes (T1D) using an insulin pump and self-monitoring blood glucose (SMBG). METHODS: This was a multinational, non-interventional study surveying 17 physicians from 11 countries. Each physician was asked to provide insuli…

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