COATI
Foundation model trained on 1 billion molecules for chemical structure encoding
Company profile
Company profile
Terray Therapeutics is pioneering a chemistry-first, AI-native approach to small molecule drug discovery through its EMMI (Experimentation Meets Machine Intelligence) platform. The company has invented proprietary hardware, built massive proprietary datasets, and designed custom AI models to fundamentally reimagine how drugs are discovered. At the core of Terray's approach is a patented ultra-dense microarray technology that has generated over 17 billion unique measurements, growing by 1 billion every quarter—creating a proprietary dataset 50x larger than all public chemistry data. This experimental foundation feeds COATI, Terray's foundation model trained on 1 billion molecules, which enables the company to explore dark areas of chemical space that traditional methods cannot access. The EMMI platform integrates generative AI for molecule design, predictive models including TerraBind for binding affinity prediction, and automated experimentation that closes the loop between design and testing. Terray has successfully screened over 90% of difficult targets to yield unique chemistry starting points and has progressed 8 AI-driven programs for undruggable targets in the past 4 years, operating 2x faster than traditional approaches. The company serves pharmaceutical and biotech partners while building its own internal pipeline, focusing on targets previously considered undruggable. Terray's multidisciplinary team combines expertise in chemistry, biology, machine learning, and automation engineering to tackle the hardest problems in drug discovery.
Company description Terray Therapeutics official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Embedded · On Premise deployment with recorded integration context.
Company milestones
TerraSynth synthesis acceleration announced June 2026; TerraBind potency prediction model introduced February 2026; Lisa L. Decker appointed Chief Business Officer June 2026; proprietary dataset reached 17+ billion measurements growing by 1 billion per quarter
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Foundation model trained on 1 billion molecules for chemical structure encoding
Chemistry-first, AI-native platform for small molecule drug discovery
Molecule selection system that quantifies prediction confidence and outperforms conventional approaches by 3x
Universal potency prediction model up to 20% more accurate and 26x faster than comparable models
Automated synthesis system for AI-designed small molecules
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
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Research
Nature communications · Jun 13, 2026
COATI: Multimodal Contrastive Pretraining for Representing and Traversing Chemical Space.Journal of chemical information and modeling · Feb 26, 2024
Synthesis of 4-(2,2-Difluorovinyl)benzonitrile through a Wittig-type Olefination of 4-Formylbenzonitrile.Organic syntheses; an annual publication of satisfactory methods for the preparation of organic chemicals · Jan 1, 2024
Paths to cheminformatics: Q&A with Phyo Phyo Kyaw Zin.Journal of cheminformatics · Feb 13, 2023
Clinical validation
No linked records are currently available.
Regulatory
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04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Screening performance
Undruggable targets in past 4 years
Evolving novel chemotypes
Small molecule discovery
EMMI Select molecule selection benchmarking
TerraBind vs comparable potency models
Ultra-fast sequence-only potency model vs public models
Screening difficult targets to yield unique chemistry starting points and progressing AI-driven programs for undruggable targets
>90% of difficult targets screened yielded unique chemistry starting points; 8 AI-driven programs progressed for undruggable targets in the past 4 years; >2x faster than traditional approaches at evolving a novel chemotype
05 · Leadership
Leadership profiles and professional links from the current Company record.
06 · Company updates
Recent articles published on Terray Therapeutics's official website.
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07 · HAIC coverage
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08 · Official presence
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09 · Market pathway
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Market context
Companies using AI, machine learning, or computational biology to discover new drug candidates, identify drug targets, predict drug efficacy, or accelerate pharmaceutical development. Includes both small molecule and biologics development, precision oncology drug discovery, and AI-driven target identification and molecule design.
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