Sempre Health Medication Adherence Platform
Behavior-based dynamic pricing platform that rewards patients with lower copays for on-time prescription refills
Platform · Cloud SaaSCompany source
Company profile
About Sempre Health
Sempre Health is a healthcare technology company that has pioneered behavior-based dynamic pricing for prescription medications. The company operates a two-sided marketplace that aligns pharmaceutical manufacturers, health plans, and patients around medication affordability and adherence. Through its SMS-based platform, Sempre engages patients with timely refill reminders and progressively lower copays as they consistently refill their medications on time. The platform requires no app downloads or passwords, making it accessible to patients across all demographics. Sempre partners with health plans to deliver white-labeled adherence interventions at no cost to the plan, with pharmaceutical manufacturers funding the discounts. The company's approach addresses medication nonadherence—a critical challenge in healthcare—by removing cost barriers and using behavioral economics principles to motivate healthy behaviors. Sempre's platform is available at all retail pharmacies across the United States and supports multiple therapeutic areas including diabetes, cardiovascular disease, and respiratory conditions. The company has demonstrated measurable outcomes including 15-25% increases in adherence rates, 45-65% reductions in out-of-pocket costs for enrolled members, and industry-leading Net Promoter Scores above 95. Sempre is backed by leading healthcare and technology investors and maintains HITRUST certification for data security.
Company description Sempre Health official website
Primary marketPharmacy & Medication Management
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint
Where the Company operates
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Clinical focus
- cardiovascular disease
- chronic conditions requiring single-source drugs
- diabetes
- respiratory conditions
Who it serves
- Health Plans
- Payers
- Pharmaceutical Manufacturers
Deployment & integration
Cloud Saas deployment with recorded integration context.
Recorded integration context: health plan systems, retail pharmacies nationwide.
Geographic context
MarketsUnited States
Company sourceOfficial website
Company milestones
Platform expansion
Prime Therapeutics expanded partnership nationwide in October 2025 after successful pilot. Blue Shield of California presented positive research results at AMCP in April 2024. Dr. John M. O'Brien joined Board of Directors in October 2025. Regence partnership announced June 2026.
Partnerships
Recorded partners
- Alluma
- Blue Cross NC
- Blue Shield of California
- Prime Therapeutics
- Regence
- regional Blues plans
- UPMC
02 · Flagship portfolio
Products, workflows, and platform capabilities
Selected source-backed Company products and the available commercial context.
03 · Research intelligence
Research Intelligence evidence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Evidence position
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Publications & preprints
Building and Scaling a Platform Business in Health Care.Journal of the American College of Radiology : JACR · Apr 1, 2025
Assessing the impact of a financial incentive and refill reminder program on medication adherence and costs.Journal of managed care & specialty pharmacy · Jan 1, 2024
MutSα mismatch repair protein stability is governed by subunit interaction, acetylation, and ubiquitination.G3 (Bethesda, Md.) · Apr 23, 2021
Clinical validation
Clinical-trial records
No linked records are currently available.
Regulatory
Regulatory records
No linked records are currently available.
04 · Company-reported outcomes
Outcomes and case studies
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
15-25% increase in adherence (PDC)
typical increase for enrolled members
45-65% out-of-pocket savings
for enrolled members over 12 months
95+ NPS
industry-leading member experience score
3.7x ROI
expected return from improved refill behavior
25-40% enrollment rate
of eligible population
4+ incremental fills
in 12 months for program participants
30% utilization rate
of patients utilizing the program
Regence
Making prescription drugs more affordable and effective for members
Partnership to keep Regence members healthy by making it easier to fill prescriptions
Prime Therapeutics and Blue Cross NC
Pilot program for behavior-based pricing model to advance patient affordability
Strong results led to nationwide expansion of partnership; significant savings found in pilot program
Blue Shield of California
Improving medication adherence and clinical outcomes for members
Research presented at Academy of Managed Care Pharmacy national meeting in April 2024 demonstrated improved medication adherence and clinical outcomes
Large Midwest Health Plan
Tackling medication nonadherence across ~93.4K members
17% increase in average PDC; 74% of Sempre members became adherent after enrolling (compared to 47% of non-Sempre members)
UPMC
Member experience improvement through medication affordability program
Member experience team consistently surprised at positive response from members
05 · Leadership
Leadership team
Leadership profiles and professional links from the current Company record.
Anurati Mathur
Co-Founder & CEO
Swaraj Banerjee
Co-Founder & CTO
Christopher Lee
VP, Strategy & Analytics
Andrew Lin
Head of Product
Elisabeth Rice
Head of People
Ryan Kuhn
Head of Partnerships & Strategy, Payers
Kyle Warner
Director, Life Sciences Partnerships
06 · Company updates
Updates from Sempre Health
Recent articles published on Sempre Health's official website.
Dr. John M. O’Brien Joins Sempre Board of Directors
Read on Sempre HealthRegence, Sempre Health partner to make prescription drugs more affordable and effective
Read on Sempre HealthPerspectives on the pharmacy landscape with Mike Einodshofer
Read on Sempre HealthPrime Therapeutics and Sempre Health Expand Innovative Behavior-Based Pricing Model to Advance Patient Affordability
Read on Sempre HealthSempre Health launches in-store savings notifications for patients, bringing discounts right to the pharmacy counter
Read on Sempre Health07 · HAIC coverage
Coverage and analysis
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Company sources and channels
Curated official destinations from the active Company record.
09 · Market pathway
Additional Companies in this Market
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Pharmacy & Medication Management
Companies using AI for medication optimization, pharmacy automation, drug pricing and access, medication adherence, polypharmacy management, or pharmacy workflow optimization. Includes platforms that help patients access affordable medications, tools that reduce medication errors, and AI systems that optimize drug regimens for complex patients.
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View all Companies in this market
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Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.