About RebrAIn, SAS
RebrAIn is a medical technology company specializing in precision brain targeting for functional neurosurgery, with a focus on deep brain stimulation (DBS) procedures for movement disorders. Founded as a spin-off of the University Hospital of Bordeaux and Inria after 10 years of academic research, the company was created by Professor Emmanuel Cuny, a neurosurgeon, and Professor Nejib Zemzemi, a researcher in applied mathematics at Inria. The company's flagship service is a supervised AI-driven solution that provides millimetric MRI-guided targeting for neurosurgical procedures. Using advanced algorithms and a health data exchange platform, RebrAIn identifies 18 anatomical landmarks per brain hemisphere to precisely locate treatment targets such as the subthalamic nucleus (STN) for Parkinson's Disease and the ventral intermediate nucleus (VIM) for Essential Tremor. The platform processes standard T1 MRI scans through a secure cloud-based system, delivering marked MRI images with target overlays within 24 hours. RebrAIn's technology aims to simplify and standardize neurosurgical procedures, potentially eliminating the need for intraoperative electrophysiology and enabling surgery under general anesthesia. This approach reduces procedure time, hospital stays, and patient trauma while maintaining high precision. The company serves neurosurgeons and hospital systems, with over 60 sites worldwide having adopted the technology and more than 1,000 targeting operations performed. RebrAIn operates with dual headquarters in France and the United States, positioning itself to serve both European and North American markets in the rapidly growing field of functional neurosurgery.
Mission & Story
Mission
To simplify and standardize neurosurgical procedures, aiming to treat more patients worldwide through precise, AI-driven brain targeting technology.
Founding Story
RebrAIn was founded as a spin-off of the University Hospital of Bordeaux and Inria after 10 years of academic research and 2 doctoral theses. The company was created by Professor Emmanuel Cuny, a functional neurosurgeon, and Professor Nejib Zemzemi, a researcher at Inria specializing in applied mathematics.
Clinical Focus
Medical conditions and clinical areas addressed by RebrAIn, SAS.
Who It Serves
Milestones & Awards
Recent Milestones
2025/2026: Transatlantic expansion focusing on major US and European neurosurgery reference centers. Partnership with Worldwide Dystonia Research Center announced May 2026 to expand from STN/VIM targeting to GPi targeting for dystonia. Brand identity launch May 2026. Top partner centers by volume include Duke University, UVA, Pamplona, and UCLA.
Key Partnerships
Social & Media
Latest Updates
Rebrain x Worldwide Dystonia Research Center
RebrAIn joins the Charter for the Responsible Development of Neurotechnologies
RebrAin 2025/2026: Expanding Reach, Driving Innovation
Rebrain unveils its identity: a strong vision for the future of assisted neurosurgery
Rebrain publishes OPTIVIM trial results in Neurosurgery
Company Details
- Headquarters
- Pessac, Nouvelle-Aquitaine, France
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