Company profile

RebrAIn, SAS

Surgical AI & Robotics

Company profile

About RebrAIn, SAS

RebrAIn is a medical technology company specializing in precision brain targeting for functional neurosurgery, with a focus on deep brain stimulation (DBS) procedures for movement disorders. Founded as a spin-off of the University Hospital of Bordeaux and Inria after 10 years of academic research, the company was created by Professor Emmanuel Cuny, a neurosurgeon, and Professor Nejib Zemzemi, a researcher in applied mathematics at Inria. The company's flagship service is a supervised AI-driven solution that provides millimetric MRI-guided targeting for neurosurgical procedures. Using advanced algorithms and a health data exchange platform, RebrAIn identifies 18 anatomical landmarks per brain hemisphere to precisely locate treatment targets such as the subthalamic nucleus (STN) for Parkinson's Disease and the ventral intermediate nucleus (VIM) for Essential Tremor. The platform processes standard T1 MRI scans through a secure cloud-based system, delivering marked MRI images with target overlays within 24 hours. RebrAIn's technology aims to simplify and standardize neurosurgical procedures, potentially eliminating the need for intraoperative electrophysiology and enabling surgery under general anesthesia. This approach reduces procedure time, hospital stays, and patient trauma while maintaining high precision. The company serves neurosurgeons and hospital systems, with over 60 sites worldwide having adopted the technology and more than 1,000 targeting operations performed. RebrAIn operates with dual headquarters in France and the United States, positioning itself to serve both European and North American markets in the rapidly growing field of functional neurosurgery.

Company description RebrAIn, SAS official website

Primary marketSurgical AI & Robotics
Commercial modelCommercial information available on request
Company presenceOfficial website
Work at RebrAIn, SAS?

Claim this profile to manage Company information and connect with the Health AI Central audience.

Claim this listing

01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Dystonia (including pediatric dystonia)
  • Essential Tremor
  • Movement disorders
  • Parkinson's Disease

Who it serves

  • Academic medical centers
  • Functional neurosurgery centers
  • Hospital systems
  • Neurosurgeons

Deployment & integration

Cloud Saas deployment with recorded integration context.

Geographic context

MarketsEurope · France · Global (60+ sites worldwide) · United States
Company sourceOfficial website

Company milestones

Platform expansion

2025/2026: Transatlantic expansion focusing on major US and European neurosurgery reference centers. Partnership with Worldwide Dystonia Research Center announced May 2026 to expand from STN/VIM targeting to GPi targeting for dystonia. Brand identity launch May 2026. Top partner centers by volume include Duke University, UVA, Pamplona, and UCLA.

Partnerships

Recorded partners

  • Duke University
  • Inria
  • Pamplona
  • UCLA
  • University Hospital of Bordeaux
  • University of Virginia (UVA)
  • Worldwide Dystonia Research Center

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

OptimDBS

AI-powered deep brain stimulation planning platform

Software · Cloud SaaSCompany source

OptimMRI

AI-driven MRI-guided brain targeting service for functional neurosurgery

Software · Cloud SaaSCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

No linked records are currently available.

Clinical validation

Clinical-trial records

No linked records are currently available.

Regulatory

Regulatory records

OptimMRI (v2)

K242054 · 510k · Aug 12, 2024

OptimMRI

K230150 · 510k · Jul 21, 2023

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

Sub-millimetric targeting precision

MRI-guided brain targeting for DBS surgery

20-30% cost savings

Hospital affordability through reduced procedure time and hospital stays

Reduced hospital stay

Simplified surgical workflow

Reduced infection rate

Less staff required in operating room

Surgery under general anesthesia

Eliminating need for intraoperative electrophysiology

24-hour turnaround

From MRI upload to marked MRI delivery

Duke University

High-volume neurosurgery center using Rebrain's AI-driven targeting service for DBS procedures

Top partner center by volume

UCLA

Leading academic medical center implementing Rebrain's AI-guided brain targeting platform

Top partner center by volume

University Hospital of Pamplona

European reference center for functional neurosurgery using Rebrain's targeting services

Top partner center by volume

University of Virginia (UVA)

Major neurosurgery reference center utilizing Rebrain's targeting services for functional neurosurgery

Top partner center by volume

60+ sites worldwide

Global adoption of AI-driven brain targeting for DBS procedures in Parkinson's Disease and Essential Tremor

1,000+ targeting operations performed across 60+ sites; 20-30% cost savings; reduced hospital stay; reduced infection rate

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

Emmanuel Cuny

Emmanuel Cuny

Co-Founder, CMO & Chairman

LinkedIn

Nejib Zemzemi

Co-Founder

06 · Company updates

Updates from RebrAIn, SAS

Recent articles published on RebrAIn, SAS's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Surgical AI & Robotics

Companies developing surgical technologies enhanced by AI, including robotic surgical systems, AI-powered surgical assistance and navigation tools, autonomous surgical robotics, and surgical data and analytics platforms. Covers both the performance of surgery and the analysis of surgical outcomes and OR efficiency.

Explore the full market directory or compare this Company with additional active profiles.

View all Companies in this market

10 · Pro research

Coming soon

Expanded Company research is in development.

Health AI Central Pro · Coming Soon

Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

Coming Soon