ACTIFY 3D Total Knee System
Cementless total knee reconstruction system
Device · On PremiseCompany source
Company profile
About Globus Medical
Globus Medical is a global medical device company focused on developing and commercializing innovative musculoskeletal solutions. The company serves surgeons and patients across three primary areas: spine procedures, orthopedic trauma, and joint reconstruction. Globus Medical's comprehensive portfolio includes procedurally integrated access systems, interbody spacers, fixation systems, plating systems, nailing systems, knee and hip reconstruction systems, and regenerative biologics. The company's Excelsius Technology ecosystem represents a leading-edge platform of robotic navigation, freehand navigation, and advanced imaging systems designed to improve safety and care in the operating room. With solutions spanning from minimally invasive spine surgery to complex deformity correction, limb reconstruction, and joint replacement, Globus Medical actively listens to the needs of surgeons and patients to solve unmet clinical needs. The company is committed to improving patient care through education, research, and clinical support, operating state-of-the-art research laboratories for in-house testing and analysis of musculoskeletal techniques and technologies. Globus Medical's mission centers on delivering procedurally integrated solutions paired with enabling technologies to change lives and improve patient outcomes across the continuum of musculoskeletal care.
Company description Globus Medical official website
Primary marketSurgical AI & Robotics
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint
Where the Company operates
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Clinical focus
- Bone fractures (clavicle, humerus, femur, tibia, ankle, radius)
- Cervical disc degeneration
- Hip and knee joint degeneration
- Limb length discrepancy
- Pediatric spinal conditions
- Sacroiliac joint disorders
- Scoliosis
- Spinal deformity
- Vertebral compression fractures
Who it serves
- Ambulatory Surgery Centers
- Healthcare Systems
- Hospitals
- Surgeons
Deployment & integration
Cloud Saas · On Premise deployment with recorded integration context.
Geographic context
MarketsAustralia · Austria · Brazil · Colombia · Germany · Hong Kong · India · Ireland · Italy · Japan · Malaysia · Mexico · New Zealand · Philippines · Singapore · Spain · Switzerland · Taiwan · Thailand · United Kingdom · United States · Vietnam
Company sourceOfficial website
Company milestones
Platform expansion
Expanded Excelsius Technology ecosystem with multiple navigation and imaging platforms. Developed comprehensive power portfolio including Verzera navigated high-speed drill and DuraPro oscillating system. Launched ACTIFY 3D Total Knee System and multiple trauma fixation systems.
Partnerships
Recorded partners
No partners are currently listed.
02 · Flagship portfolio
Products, workflows, and platform capabilities
Selected source-backed Company products and the available commercial context.
ACTIFY Total Knee System
Total knee system mimicking native knee kinematics
Device · On PremiseCompany source
ACTIFY Unicondylar Knee System
Partial knee replacement system for enhanced surgical efficiency
Device · On PremiseCompany source
DuraPro Oscillating System
Oscillating surgical system for bone preparation
Device · On PremiseCompany source
Excelsius3D
3D imaging and visualization for surgical planning
Device · On PremiseCompany source
ExcelsiusFlex
Freehand navigation system for surgical guidance
Device · On PremiseCompany source
ExcelsiusGPS
Robotic navigation platform for spine and cranial surgery
Device · On PremiseCompany source
ExcelsiusHub
Central integration platform for Excelsius Technology ecosystem
Platform · On PremiseCompany source
ExcelsiusXR
Advanced imaging system for surgical procedures
Device · On PremiseCompany source
03 · Research intelligence
Research Intelligence evidence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Evidence position
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Publications & preprints
Safety of Transcranial Motor-Evoked Potential Linked Quadripolar Montage.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · Apr 1, 2026
Biomechanical comparison of triangular osteosynthesis and triangular minimally invasive spinopelvic stabilization technique for pelvic fragility fractures.Injury · Mar 1, 2026
Leg muscle microvascular function is associated with dynamic but not static balance performance in older adults.BMC geriatrics · Feb 23, 2026
Bridging the Gap Between Species: Translating a Fracture Callus Mechanical Properties Model From Ovine to Human Use.Journal of biomechanical engineering · Feb 1, 2026
Construct-construct "rail technique" decreases screw strain during spinal deformity corrective maneuvers across a thoracic vertebral column resection: a cadaveric analysis.Spine deformity · Jan 1, 2026
A Biomechanical Comparison of Alternatives to C2 Pedicle Screws.Spine · Dec 15, 2025
Clinical validation
Clinical-trial records
A Retrospective Review: Outcomes of the REFLECT™ System for Idiopathic ScoliosisNCT07589023 · Sponsor · NOT YET RECRUITING
Complex Adult Deformity Surgery (CADS)NCT04194138 · Sponsor · RECRUITING
REFLECT Scoliosis System Post Approval StudyNCT06298812 · Sponsor · RECRUITING
Post-Approval Study Protocol for the Simplify Cervical Artificial DiscNCT04630626 · Sponsor · COMPLETED
Post Approval Study Protocol for the Two Level Simplify® Cervical Artificial DiscNCT04980378 · Sponsor · COMPLETED
Investigation of the Simplify® Cervical Artificial DiscNCT02667067 · Sponsor · COMPLETED
Regulatory
Regulatory records
No linked records are currently available.
04 · Company-reported outcomes
Outcomes and case studies
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
No Company-reported outcomes are currently listed.
05 · Leadership
Leadership team
Leadership profiles and professional links from the current Company record.
No active leadership profiles are currently listed.
06 · Company updates
Updates from Globus Medical
Recent articles published on Globus Medical's official website.
No Company updates are currently listed.
07 · HAIC coverage
Coverage and analysis
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Company sources and channels
Curated official destinations from the active Company record.
09 · Market pathway
Additional Companies in this Market
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Surgical AI & Robotics
Companies developing surgical technologies enhanced by AI, including robotic surgical systems, AI-powered surgical assistance and navigation tools, autonomous surgical robotics, and surgical data and analytics platforms. Covers both the performance of surgery and the analysis of surgical outcomes and OR efficiency.
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10 · Pro research
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Expanded Company research is in development.
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Deeper Company research is coming soon.
Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.
Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.