Chroma
Generative AI platform for designing novel therapeutic proteins
Company profile
Generative AI for therapeutic protein design and drug discovery
Company profile
Generate Biomedicines is a biotechnology company at the forefront of applying generative artificial intelligence to therapeutic protein design and drug discovery. The company has developed a proprietary generative biology platform that uses machine learning to create novel protein therapeutics from scratch, rather than modifying existing proteins. This approach enables the design of proteins with specific therapeutic properties tailored to address unmet medical needs. Generate Biomedicines' technology platform combines deep learning, structural biology, and computational protein design to generate and optimize therapeutic candidates across multiple modalities including antibodies, peptides, and other protein-based drugs. The company's mission is to expand the druggable proteome and accelerate the development of breakthrough medicines. By leveraging generative AI, Generate Biomedicines aims to design proteins that are difficult or impossible to create using traditional methods, potentially unlocking new therapeutic opportunities across various disease areas. The company serves the biopharmaceutical industry and is developing its own pipeline of therapeutic candidates while also partnering with pharmaceutical companies to apply its platform to their drug discovery programs.
Company description Generate Biomedicines official website
Mission. Democratizing biotherapeutics and pioneering generative biology to create breakthrough medicines.
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01 · Operating footprint
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Company milestones
Initiated global Phase 3 studies of GB-0895 for severe asthma. Reported Q1 2026 financial results. Expanded to 140,000+ square feet across Boynton Yards (Somerville) and Andover locations. Participated in Goldman Sachs 47th Annual Global Healthcare Conference (May 2026).
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02 · Flagship portfolio
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Generative AI platform for designing novel therapeutic proteins
03 · Research intelligence
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Research
CPT: pharmacometrics & systems pharmacology · Oct 1, 2026
Randomized, Double-Blind, Placebo-Controlled First-in-Human Trial of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix.The Journal of infectious diseases · Jul 14, 2026
Persistence of memory: lifespan dynamics of the human antiviral antibody reactome.Nature communications · Jun 22, 2026
Chemically induced skin tumors arise from long-lived stem cells of the upper hair follicle.Science (New York, N.Y.) · Jun 11, 2026
The immunogenicity database collaborative: a standardized, publicly available database for clinical immunogenicity observations and insights.Frontiers in immunology · Jan 1, 2026
Characterizing Phytochrome Photochemistry Using UV-Visible Spectroscopy in Host Cell Extracts and Purified Protein.Methods in molecular biology (Clifton, N.J.) · Jan 1, 2026
Clinical validation
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Regulatory
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04 · Company-reported outcomes
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05 · Leadership
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Michael Nally
Chief Executive Officer
Gevorg Grigoryan
Co-Founder & Chief Technology Officer
Jason Silvers
President & Chief Financial Officer
Aarif Khakoo
Chief Scientific Officer
Laurie Lee
Chief Medical Officer, Immunology & Inflammation
Sean Martin
Chief Legal Officer & General Counsel
Beth Grous
Chief People Officer
Dinesh de Alwis
Senior Vice President, Head of Clinical Drug Development
06 · Company updates
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07 · HAIC coverage
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08 · Official presence
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09 · Market pathway
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Market context
Companies using AI, machine learning, or computational biology to discover new drug candidates, identify drug targets, predict drug efficacy, or accelerate pharmaceutical development. Includes both small molecule and biologics development, precision oncology drug discovery, and AI-driven target identification and molecule design.
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