Fabric Genomics

Company profile

About Fabric Genomics

Fabric Genomics is making precision medicine a reality by facilitating clinical labs, hospital systems, and country-sequencing programs to develop, deploy, and scale genomic testing. The company's flagship Fabric Enterprise platform leverages advanced AI algorithms to automate genomic data interpretation and generate physician-ready clinical reports for any genomic test. Fabric's technology addresses the major bottleneck in genetic testing: interpretation and report generation as test volumes rapidly increase. The platform combines deep phenotype data with genotype data using machine learning to accurately identify and prioritize disease-causing variants in rare idiopathic diseases. Fabric's AI approach includes proprietary algorithms such as GEM, VAAST, Phevor, and VVP that systematically prioritize variants based on severity in conjunction with patient phenotype. The company serves children's hospitals, hospital systems, and commercial laboratories worldwide, supporting applications including hereditary risk screening, rare disease diagnosis, rapid NICU testing, pediatric panels, and country genome projects. Fabric's cloud-based solution can scale from a single test to hundreds of thousands while maintaining high accuracy and rapid turnaround times. The company has achieved diagnostic yields up to 50% compared to the industry average of 25-30%, with the ability to generate clinical reports in less than two hours for whole genome sequence data. In a significant milestone, GeneDx acquired Fabric Genomics to expand decentralized, AI-powered testing at global scale.

Company description · Fabric Genomics official website