Company profile

Exact Sciences

Precision Medicine & Genomics

Company profile

About Exact Sciences

Exact Sciences is a leading molecular diagnostics company dedicated to eradicating cancer through prevention, early detection, and personalized treatment guidance. Founded in 1995 and headquartered in Madison, Wisconsin, the company has grown to serve over 120 countries with more than 6,500 employees globally. Exact Sciences develops and commercializes innovative cancer tests that explore hereditary risks, screen for cancer's presence, and examine the unique genomic alterations of an individual's cancer to help guide treatment decisions. The company's portfolio includes the widely-adopted Cologuard colorectal cancer screening test, the Oncotype DX suite of genomic tests for breast and colon cancer treatment guidance, and newer innovations like the Cancerguard multi-cancer early detection test. With nine research and development centers and state-of-the-art laboratories, Exact Sciences combines rigorous research, deep clinical expertise, and proven accuracy to deliver life-changing diagnostic solutions. The company has tested over 4 million people in 2023 alone and maintains strong collaborations with leading medical institutions, advocacy partners, and policymakers. Exact Sciences went public in February 2001 and has been certified as a Great Place to Work for seven consecutive years, reflecting its commitment to innovation, integrity, quality, teamwork, and accountability in the fight against cancer.

Company description Exact Sciences official website

Primary marketPrecision Medicine & Genomics
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint

Where the Company operates

Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.

Clinical focus

  • Breast cancer
  • Colorectal cancer
  • DCIS (Ductal Carcinoma In Situ)
  • Liver cancer
  • Molecular residual disease
  • Multi-cancer screening
  • Stage II-IV cancers

Who it serves

  • Health Systems
  • Healthcare Providers
  • Patients/Consumers
  • Payers

Deployment & integration

Other deployment with recorded integration context.

Geographic context

Markets120+ countries globally · France · Germany · Italy · Japan · Poland · United Kingdom · United States
Company sourceOfficial website

Company milestones

Platform expansion

Launch of three innovative cancer tests in 2025; Publication of BLUE-C study results in 2024; OncoExTra cancer therapy selection test launch in 2023; PreventionGenetics acquisition in 2022

Partnerships

Recorded partners

  • Advocacy partners
  • Leading medical institutions
  • National Cancer Center of Japan
  • Policymakers
  • University of Pittsburgh Medical Center (UPMC)

02 · Flagship portfolio

Products, workflows, and platform capabilities

Selected source-backed Company products and the available commercial context.

Cancerguard

Innovative multi-cancer early detection test

Software · OtherCompany source

Cologuard

Non-invasive colorectal cancer screening test

Device · OtherCompany source

Cologuard Plus

Enhanced colorectal cancer screening test

Device · OtherCompany source

Oncodetect

Molecular residual disease detection test

Software · OtherCompany source

Oncotype DX Breast DCIS Score

Genomic test for ductal carcinoma in situ

Software · OtherCompany source

Oncotype DX Breast Recurrence Score

Genomic test for breast cancer treatment decisions

Software · OtherCompany source

Oncotype DX Colon Recurrence Score

Genomic test for colon cancer recurrence risk

Software · OtherCompany source

03 · Research intelligence

Research Intelligence evidence

Publications, preprints, clinical validation, and regulatory records in Evidence Position order.

Evidence position

Publications, clinical validation, and regulatory records connected to this Company appear here.

Research

Publications & preprints

Raman quantification of (R)-(+)-limonene in mineral oil: An integrated PCA/PLS and DFT-PED approach.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · Dec 15, 2026

Clinical and economic benefits of combined genetic and genomic testing strategies to guide treatment decisions for patients with HR+/HER2- breast cancer in the US.

Journal of medical economics · Dec 1, 2026

Model-based evaluation of colorectal cancer screening effectiveness: three rounds of multitarget stool DNA testing versus one colonoscopy.

Journal of medical economics · Dec 1, 2026

Costs and benefits of whole-exome, whole-transcriptome sequencing versus 50-gene panels for genomic profiling in solid tumors.

Journal of medical economics · Dec 1, 2026

High-resolution chemical characterization and bioactivity assessment of Solanum cernuum infusion.

Journal of ethnopharmacology · Nov 15, 2026

Experimental and theoretical investigation of photoinduced electronic transitions and charge-transfer properties in a novel azo compound: (E)-1-((3-Methoxyphenyl)diazenyl)naphthalen-2-ol.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy · Nov 5, 2026

Clinical validation

Clinical-trial records

Endometrial Cancer Vaginal Fluid Specimen Collection Study

NCT07544680 · Sponsor · RECRUITING

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

NCT05410977 · Sponsor · RECRUITING

Patient Reminders Optimizing Mail-in Prevention Testing for Colorectal Cancer

NCT06710509 · Mentioned · COMPLETED

Assessment of a Minimally Invasive Collection Device for Molecular Analysis of Esophageal Samples

NCT06071845 · Mentioned · RECRUITING

Falcon Real World Evidence Registry

NCT06589310 · Sponsor · RECRUITING

Head to Head Pilot Trial of Mailed Cologuard to Mailed FIT

NCT06173375 · Mentioned · COMPLETED

Regulatory

Regulatory records

No linked records are currently available.

04 · Company-reported outcomes

Outcomes and case studies

Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.

94% specificity for colorectal neoplasia

Age-weighted to U.S. population for adults with no colorectal neoplasia

4M+ people tested in 2023

Global testing volume

University of Pittsburgh Medical Center (UPMC)

ALPHA-CORRECT study investigating ctDNA association with recurrence in stage III colorectal cancer

Demonstrated association of ctDNA with recurrence risk using Oncodetect test

Deepa (Breast Cancer Surgeon)

Genomic testing helped guide treatment decision to forgo chemotherapy for breast cancer

Informed decision to forgo chemotherapy based on genomic test results

Leigh Anne

At-home testing enabled early detection and treatment of colon cancer before progression

Early detection and treatment of colon cancer before progression

National Cancer Center of Japan

BETA-CORRECT study investigating ctDNA association with recurrence in stage II-IV colorectal cancer

Demonstrated association of ctDNA with recurrence at pre-specified timepoints using Oncodetect test

05 · Leadership

Leadership team

Leadership profiles and professional links from the current Company record.

06 · Company updates

Updates from Exact Sciences

Recent articles published on Exact Sciences's official website.

07 · HAIC coverage

Coverage and analysis

Health AI Central reporting that mentions this Company.

No HAIC coverage is currently linked to this Company.

08 · Official presence

Company sources and channels

Curated official destinations from the active Company record.

09 · Market pathway

Additional Companies in this Market

Other active Companies in the same market, selected alphabetically from the HAIC directory.

Market context

Precision Medicine & Genomics

Companies using AI to analyze genomic, proteomic, metabolomic, or multi-omics data to provide personalized treatment recommendations, identify genetic risks, or develop targeted therapies. Includes genomic sequencing platforms with AI analysis, preventive medicine based on genetic risk assessment, and longevity care based on molecular and genetic data.

Explore the full market directory or compare this Company with additional active profiles.

View all Companies in this market

10 · Pro research

Coming soon

Expanded Company research is in development.

Health AI Central Pro · Coming Soon

Deeper Company research is coming soon.

Pro Research will introduce expanded technical context, linked evidence analysis, and comparative Company research.

ResearchEvidence analysis

Linked research, clinical, and regulatory source pathways.

CompanyTechnical context

Expanded product, deployment, integration, and partnership research.

MethodSource & review record

Record-level provenance and review context.

Coming Soon