Dante Labs

Dante Labs

Precision Medicine & Genomics

About Dante Labs

Dante Labs is a clinical genomics company that makes whole genome sequencing accessible to individuals and healthcare providers worldwide. Founded in 2016 and headquartered in New York City, the company has sequenced over 100,000 genomes and delivered more than 1.3 million clinical reports to customers in over 100 countries. Dante Labs sequences the entire genome—not just targeted gene panels—at 30X coverage with 99.98% accuracy in ISO 15189-accredited, CLIA-certified, and CAP-accredited laboratories in Europe and the United States. The company's approach addresses situations where standard genetic testing falls short: hereditary conditions that run in families, unexplained symptoms with no clear diagnosis, treatments that aren't working as expected, and proactive health planning. Each genome test generates over 200 physician-ready clinical reports organized by category, including cardiovascular, hereditary cancer, neurological, rare diseases, metabolic, pharmacogenomics, and autoimmune conditions. Results are classified to ACMG standards—the same framework used by major medical institutions—and are automatically updated as new variant-disease associations are discovered. The company also offers RNA profiling and oncology-specific genomic analysis. Dante Labs' mission is to make comprehensive genomic information clinically actionable, helping patients and physicians make informed decisions together. The company has documented clinical outcomes where its genomic data enabled diagnoses at NHS hospitals and changed treatment plans for conditions including Noonan Syndrome, RUNX1 deficiency, GLUT-1 epilepsy, and chemotherapy selection in breast cancer patients.

Mission & Story

Mission

Make whole genome sequencing clinically accessible—with results a physician can act on, at a cost that doesn't require institutional backing

Founding Story

Co-founded by Andrea Riposati in 2016 after seeing how long it took clinical genomics to reach the people who needed it most. Before Dante, Andrea launched 3D Printing at Amazon, built marketplace algorithms at Amazon Business, and consulted at Booz & Company. He holds an MBA from Harvard Business School and was on the teaching faculty at Harvard's Department of Economics. The company name reflects the founding intent—'Dante' after the Italian poet who made the complex comprehensible; 'Labs' for the clinical science that makes it possible.

Clinical Focus

Medical conditions and clinical areas addressed by Dante Labs.

Cardiovascular diseasesHereditary cancerNeurological conditionsRare diseasesMetabolic disordersEpilepsyNoonan SyndromeRUNX1 deficiencyGLUT-1 deficiencyLong QT SyndromeCongenital deafnessGJB2-related hearing loss

Who It Serves

Individual consumersPatients with hereditary riskPatients with unexplained symptomsCancer patientsProactive health consumersPhysiciansClinical teams

Milestones & Awards

Recent Milestones

Over 100,000 genomes sequenced. Documented clinical outcomes with NHS genetics teams. CEO Andrea Riposati presented at Italian Tech Week 2023. Recognition in Financial Times Top 25 European Fastest Growing Companies and Sole 24 Ore Growth Leaders.

Awards & Recognition

EY Entrepreneur of the Year 2019 (Andrea Riposati). Financial Times Top 25 European Fastest Growing Companies. Sole 24 Ore Growth Leaders. Forbes Technology Council member (Andrea Riposati).

Key Partnerships

NHS (documented clinical case acceptance at Queen Elizabeth University Hospital Glasgow)Nature Communications (publication partner)American Society of Human GeneticsInternational Society for Cell & Gene TherapyGene Journal

Company Details

Founded
2016
Headquarters
New York City, NY, USA

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Security & Compliance

CLIACAPISO 15189HIPAAGDPRACMG

Official Sources

Last updated Jun 28, 2026

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