1:1 Direct Messaging
Text-first approach for personalized patient communication and care coordination
Company profile
Company profile
CareMessage is a technology nonprofit organization building the largest patient engagement platform specifically designed for low-income populations in the United States. Since 2013, CareMessage has reached 20 million patients and exchanged over 500 million messages across 45 U.S. states and territories, making it the only patient engagement solution proven to improve health equity at scale. The platform serves as a comprehensive Health Equity Engine that works alongside healthcare staff to scale population health initiatives. CareMessage offers end-to-end patient lifecycle messaging, from appointment reminders and recall campaigns to health coaching and closed-loop referrals. The platform integrates with all major EHR systems through HL7, FHIR, API, and SFTP connections, enabling data-powered patient segmentation and precision engagement. CareMessage's patented technology enables flexible patient targeting and automated engagement workflows while maintaining a human touch. The platform includes AI-powered features like response assistants and automated rescheduling, paired with clinically-validated content built from millions of patient interactions. The organization primarily serves Federally Qualified Health Centers (working with 1 in 7 FQHCs nationwide), free and charitable clinics, tribal health organizations, and primary care associations. As a nonprofit, CareMessage reinvests revenue into impact, with many team members having lived experiences in the communities they serve. The organization has received backing from the OpenAI Foundation and recognition including TIME's 2026 Impact in Equality Award and placement on the TIME100 Most Influential Companies List.
Company description CareMessage official website
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01 · Operating footprint
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Cloud Saas deployment with recorded integration context.
Recorded integration context: All major EHRs, API, Cerner, Epic, FHIR, HL7, SFTP.
Company milestones
Received backing from OpenAI Foundation (2026). Named TIME's 2026 Impact in Equality Award recipient and TIME100 Most Influential Companies List (April 2026). Named to Inc.'s 2025 Best in Business List (December 2025). Launched Wellness Copilot for diabetes management (November 2025). Launched Outreach Insights feature (July 2025). Published Stanford study in JAMA Network Open (September 2025). Received third place in CTIA Wireless Foundation's Catalyst 2025 (September 2025). Hosted inaugural Connected by Care 2025 Summit (October 2025).
Partnerships
02 · Flagship portfolio
Selected source-backed Company products and the available commercial context.
Text-first approach for personalized patient communication and care coordination
Generative AI to categorize patient responses and identify messages requiring attention
End-to-end appointment management from scheduling to follow-up
Patient engagement platform for low-income populations and safety-net healthcare organizations
Smarter patient outreach analytics for healthier communities
Support patients through follow-up care journey and close referral loops
Evidence-based AI-powered coaching programs proven to improve clinical outcomes
Data-powered patient segmentation and precision engagement for quality measures
Flexible solutions for social determinants of health screening and resource connection
03 · Research intelligence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Journal of medical Internet research · May 13, 2026
Promoting Physical Activity With Text Messaging: Does Advisor Personalization Matter?American journal of health promotion : AJHP · Feb 11, 2026
Human Telephone vs Text Message Counseling and Physical Activity Among Midlife and Older Adults: A Randomized Clinical Trial.JAMA network open · Sep 2, 2025
Implementing texting programs in the P.O.W.E.R. (preventing obesity with eating right) medical group visit for weight loss.Obesity science & practice · Oct 1, 2021
Testing the effectiveness of physical activity advice delivered via text messaging vs. human phone advisors in a Latino population: The On The Move randomized controlled trial design and methods.Contemporary clinical trials · Aug 1, 2020
Text messaging approach improves weight loss in patients with nonalcoholic fatty liver disease: A randomized study.Liver international : official journal of the International Association for the Study of the Liver · May 1, 2018
Clinical validation
NCT03487692 · Sponsor · COMPLETED
Interactive Mobile Health Information to Enhance Patient Care at a Cystic Fibrosis CenterNCT03052231 · Mentioned · COMPLETED
Text Based Mobile Technology and Weight LossNCT03203655 · Mentioned · COMPLETED
Controlling Hyperglycemia Among Minority PopulationNCT02681718 · Mentioned · COMPLETED
Regulatory
No linked records are currently available.
04 · Company-reported outcomes
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Since 2013 across safety-net organizations
Total platform engagement
Geographic reach
Market penetration in federally qualified health centers
Health coaching programs for diabetes management
Text-based health coaching matching human counselor outcomes
Text-based health coaching to boost physical activity
CareMessage's text-based health coaching matched human counselors in boosting physical activity
Leveraged Conversational AI via Wellness Copilot for Diabetes to drive engagement of previously unengaged patients
Over 55% of previously unengaged patients requested an appointment; up to 20 hours saved per week; over 40% of patients expressed interest in booking an appointment
Health coaching programs for diabetes management
Up to 2 point reductions in A1c through health coaching programs
Improve ability to drive revenue, financially sustain operations, and improve clinical outcomes for value-based care
Working with 1 in 7 FQHCs nationwide
Maximize use of staff and volunteer time while increasing community reach
Over 200 free and charitable clinics and charitable pharmacies served nationwide
05 · Leadership
Leadership profiles and professional links from the current Company record.
No active leadership profiles are currently listed.
06 · Company updates
Recent articles published on CareMessage's official website.
07 · HAIC coverage
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Curated official destinations from the active Company record.
09 · Market pathway
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Companies using AI to engage patients, provide health education, facilitate peer support, offer AI health coaching, or help patients navigate their healthcare journey. Includes patient communities, AI health mentors, peer support networks, and platforms that empower patients to take an active role in managing their own health.
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Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.