Clinical Pathways
Highly-integrated and adaptable clinical decision support embedded in EHR workflows
Platform · Cloud SaaSCompany source
Company profile
About AgileMD
AgileMD is a clinical decision support platform that helps hospitals and health systems reduce clinical burden while improving patient outcomes. The company's flagship products include eCART, an FDA-cleared AI-powered early warning system that predicts and prioritizes clinical deterioration, and Clinical Pathways, a highly-integrated guidance system that standardizes care delivery across healthcare organizations. eCART was developed from over a decade of research and trained on nearly 3 million patient encounters from 28 hospitals across 6 health systems, with validation across sepsis, COPD, CHF, and COVID populations. The platform helps care teams identify high-risk patients early, reducing mortality, length of stay, and direct variable costs while minimizing alarm fatigue. AgileMD's Clinical Pathways solution enables rapid deployment of evidence-based protocols that integrate seamlessly with native EHR workflows, allowing clinical teams to standardize care without heavy IT support. More than 4,800 pathways are live across partner institutions, covering adult, pediatric, and neonatal care in ambulatory, emergency, inpatient, ICU, and women's health settings. The platform serves over 150,000 clinical users across 400+ hospitals, supporting more than 4.4 million patient encounters. AgileMD's approach is backed by 88+ peer-reviewed publications demonstrating clinical and operational improvements, and the platform is SOC-II and HIPAA compliant with enterprise-grade security architecture.
Company description AgileMD official website
Primary marketPopulation Health & Healthcare Analytics
Commercial modelCommercial information available on request
Company presenceOfficial website
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01 · Operating footprint
Where the Company operates
Company-profile context for clinical focus, customers, deployment, integration, milestones, and partnerships.
Clinical focus
- CHF
- Clinical deterioration (all-cause)
- Community-acquired pneumonia
- COPD
- COVID-19
- Enteral access
- Palliative care
- Pulmonary embolism
- Sepsis
Who it serves
- Academic Medical Centers
- Emergency Departments
- Health Systems
- Hospitals
- ICUs
Deployment & integration
Cloud Saas deployment with recorded integration context.
Recorded integration context: Clinical documentation systems, EHR labs and vitals, EHR systems (embedded workflows), Native EHR order sets.
Geographic context
MarketsUnited States
Company sourceOfficial website
Company milestones
Platform expansion
Multiple peer-reviewed publications in 2024-2025 from partner health systems demonstrating clinical outcomes improvements. Platform now supports 4,425,000+ patient encounters across 400+ hospitals with 150,000+ clinical users and 4,800+ live pathways.
Partnerships
Recorded partners
- Children's Hospital Colorado
- UCHealth
- UChicago Medicine
- Vanderbilt Health
- Yale New Haven Health System
02 · Flagship portfolio
Products, workflows, and platform capabilities
Selected source-backed Company products and the available commercial context.
eCART
FDA-cleared AI for clinical deterioration early warning and workflow management
Software · Cloud SaaSCompany source
03 · Research intelligence
Research Intelligence evidence
Publications, preprints, clinical validation, and regulatory records in Evidence Position order.
Evidence position
Publications, clinical validation, and regulatory records connected to this Company appear here.
Research
Publications & preprints
Multicenter Development and Prospective Validation of eCARTv5: A Gradient-Boosted Machine-Learning Early Warning Score.Critical care explorations · Apr 1, 2025
Early Warning Scores With and Without Artificial Intelligence.JAMA network open · Oct 1, 2024
Evaluation of computer-based training and high-fidelity simulation to improve early recognition of sepsis on the adult general ward.Nursing open · Jul 1, 2023
Clinical validation
Clinical-trial records
Evaluation of Pediatric eCART ImplementationNCT06771830 · Sponsor · RECRUITING
A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine LearningNCT05893420 · Sponsor · ACTIVE NOT RECRUITING
Regulatory
Regulatory records
eCARTv5 Clinical Deterioration Suite (eCART)K233253 · 510k · Jun 21, 2024
04 · Company-reported outcomes
Outcomes and case studies
Company-reported outcomes and customer stories are distinct from linked Research Intelligence evidence.
Decreased mortality
Timely ICU transfer for high-risk patients
2-day reduction in length of stay
High-risk patients transferred in timely manner
3% increase in mortality odds per hour
Delayed ICU transfer
1.5-day reduction in hospital LOS
PE pathway implementation at YNHHS
3.3-day reduction in hospital LOS
Palliative care pathway at Yale New Haven
2.9-hour reduction in ED LOS
Hospice care pathway at UCHealth
Reduced direct variable costs
eCART implementation
$1,256 cost savings per patient
Palliative care pathway at Yale
$189,000 annual cost avoidance
PE pathway at YNHHS
Yale New Haven Health
Implemented Surprise Question clinical pathway in emergency department to trigger early palliative care consultation and improve end-of-life care
Average time from admission to PC consult decreased by 1.1 days (5.7 to 4.6 days), hospital LOS reduced by 3.3 days (16.2 to 12.9 days), estimated cost savings of $1,256 per patient representing total savings of $7,611,300
Vanderbilt Health
Implemented EHR-based sepsis treatment pathway with targeted best practice alerts to improve SEP-1 bundle compliance across four-hospital system
SEP-1 bundle compliance improved from 23% to 62% at main adult ED with similar improvements mirrored at three community sites
Children's Hospital Colorado
Revised EHR-integrated clinical pathway for pediatric community-acquired pneumonia to increase evidence-based prescribing across 5 emergency departments and 5 urgent care facilities
Amoxicillin prescribing increased from 60.6% to 70.9%, azithromycin prescribing decreased from 12.5% to 3.7%, and durations for 5 days or fewer increased from 2.0% to 66.1%
UCHealth
Implemented EHR-embedded clinical pathway for chest pain patients presenting to ED with suspected acute coronary syndrome
Hospital admission frequency declined from 28.2% to 20.9%, stress testing declined from 15.8% to 12.7%, pathway associated with significant reduction in hospital admissions (-10.79%) and stress testing (-6.05%)
Yale New Haven Health System
Implemented enteral access clinical pathway to increase nutrition consults and decrease ED visits, readmissions, and overall length of stay
More likely to receive nutrition consult (52.4% vs 48.0%), less likely to re-present to ED (31.9% vs 42.6%), less likely to be readmitted (31.0% vs 41.6%)
UChicago Medicine
Developed OUD workgroup, consult service, and pathway to guide clinicians on appropriate prescribing of buprenorphine-naloxone or methadone for patients with opioid use disorder
296 OUD consults from July 2020 to April 2021, 35% received and discharged with buprenorphine, 40% managed with methadone and linked to outpatient care, naloxone dispensing at discharge increased to over 65%, patients without consult had higher readmission rates (14.9% vs 18.1%)
05 · Leadership
Leadership team
Leadership profiles and professional links from the current Company record.
No active leadership profiles are currently listed.
06 · Company updates
Updates from AgileMD
Recent articles published on AgileMD's official website.
07 · HAIC coverage
Coverage and analysis
Health AI Central reporting that mentions this Company.
No HAIC coverage is currently linked to this Company.
08 · Official presence
Company sources and channels
Curated official destinations from the active Company record.
09 · Market pathway
Additional Companies in this Market
Other active Companies in the same market, selected alphabetically from the HAIC directory.
Market context
Population Health & Healthcare Analytics
Companies providing AI-powered analytics for population health management, healthcare data integration and analysis, risk stratification, care gap identification, or value-based care analytics. Focuses on analyzing data across patient populations to improve outcomes at scale and enable data-driven decision-making across health systems.
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Expanded Company research is in development.
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Deeper Company research is coming soon.
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Linked research, clinical, and regulatory source pathways.
Expanded product, deployment, integration, and partnership research.
Record-level provenance and review context.