Peer-Reviewed Publication
N Engl J Med2026October 14, 2026Journal Article

Continuous Glucose Monitoring in Non-Insulin-Treated Type 2 Diabetes.

Tamara K Oser1, Thomas Martens2, Katrina J Ruedy3, Simon Bergford3, Peter Calhoun3, Ku-Lang Chang4, Erik S Kramer5, Beth A Klug6, R Lacy Anderson7, Benjamin R Cook8, David Pickering9, Martin Ortega10, Bryce Peterson11, Lisa Davidson12, Rita Schmid13, Nitinchandra D Desai14, Edwin Burkett15, Jamie L Haynes16, Amir Herman17, Shehzad M Topiwala18, Ryan Bailey3, Sean M Oser5, Nelly N Cadet19, Matthew L Johnson19, Karen E Elkind-Hirsch19, Stayce E Beck19, Jessica R Castle19, Roy W Beck3,
1Department of Family Medicine, University of Colorado Anschutz School of Medicine, Aurora.
2International Diabetes Center, HealthPartners Institute, Minneapolis.
3Jaeb Center for Health Research, Tampa, FL.
4Centricity Research, Morehead City, NC.
5University of Colorado, Anschutz Medical Campus, Department of Family Medicine, Primary Care Diabetes Lab, Aurora.
6Riverside Family Medicine Residency, Newport News, VA.
7Tekton Research, Moore, OK.
8Jefferson City Medical Group, Jefferson City, MO.
9Mountain State Diabetes, Parkersburg, WV.
10Texas Tech University Health Sciences Center, Odessa.
11Cope Family Medicine-Avacare Clinical Research Network, Bountiful, UT.
12Tekton Research, Denver.
13South Bend Clinic-Avacare Clinical Research Network, South Bend, IN.
14Cross Creek Medical Center, Fayetteville, NC.
15Alliance Medical Ministry, Raleigh, NC.
16Texas Tech University Health Sciences Center, Lubbock.
17East Northport Medical Care, East Northport, NY.
18Institute of Endocrinology, Diabetes, Health and Hormone, Stockbridge, GA.
19Dexcom, San Diego, CA.

Abstract

BACKGROUND: Continuous glucose monitoring (CGM) has been shown to be beneficial in persons with type 1 diabetes and others with insulin-treated type 2 diabetes, but its role in the treatment of persons with type 2 diabetes not being treated with insulin has needed further study. METHODS: In a 26-week trial conducted at 22 primary care practices in the United States, we randomly assigned adults wi…

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