Peer-Reviewed Publication
J Magn Reson Imaging2026October 1, 2026Journal Article
Diffusion Tensor Imaging of Knee Cartilage for Detection of Early Osteoarthritis and Prediction of Radiographic Progression.
José G Raya1,2, Dimitri Martel1,2, Alejandra Duarte3, Jenny T Bencardino4, Svetlana Krasnokutsky-Samuels5, Jonathan Samuels5, Richard Kijowski6, Amparo Ruiz1,2
1Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.
2Tech4Health Institute, New York University Langone Health, New York, New York, USA.
3Division of Musculoskeletal Radiology, Department of Radiology, Fundación Santa Fe de Bogotá, Bogotá, Colombia.
4Department of Radiology, Montefiore Medical Center, Bronx, New York, USA.
5Division of Rheumatology, Department of Medicine, NYU Grossman School of Medicine, NYU Langone Health, New York, New York, USA.
6RadNet, New York, New York, USA.
Abstract
BACKGROUND: The progression of early osteoarthritis (OA) is difficult to predict radiographically. T2 mapping provides information about cartilage degeneration, but its sensitivity to early matrix injury is limited. Diffusion tensor imaging (DTI) may detect cartilage microstructural abnormalities beyond T2 mapping.
PURPOSE: To test whether baseline cartilage DTI metrics are associated with early…
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