Mixed neuroendocrine-non-neuroendocrine neoplasms, amphicrine-like carcinoma and related lesions: a review of changes in classification and current concepts.

Runjan Chetty¹, Anthony J Gill²

¹Diagnexia Pty Ltd, Oxford, UK.

²Royal North Shore Hospital, University of Sydney, Sydney, New South Wales, Australia.

Abstract

To trace the historical evolution of gastrointestinal mixed epithelial-neuroendocrine tumour terminology, clarify current diagnostic criteria, histological features and approach to reporting these lesions in accordance with the latest classification of gastrointestinal tumours, a narrative overview was undertaken on mixed neuroendocrine-non-neuroendocrine neoplasia (MiNEN). The review traces termi…

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