Peer-Reviewed Publication
J Pediatr2026;115342.September 28, 2026Journal Article

Cerebral Oxygenation is Associated with Neurodevelopmental Outcome in Infants Born Preterm with Intraventricular Hemorrhage.

Julia Elis1, Renate Fuiko2, Vito Giordano3, Gregor Kasprian4, Christa Nöhammer5, Roxane Licandro6, Klemens Vierlinger7, Monika Olischar8, Angelika Berger9, Katharina Goeral10
1Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: Julia.elis@meduniwien.ac.at.
2Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: renate.fuiko@meduniwien.ac.at.
3Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: vito.giordano@meduniwien.ac.at.
4Medical University of Vienna, Department of Radiology, Division of Neuroradiology and Musculoskeletal Radiology, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: gregor.kasprian@meduniwien.ac.at.
5AIT Austrian Institute of Technology GmbH, Center Health & Bioresources, Competence Unit Molecular Diagnostics, Giefinggasse 4, 1210 Vienna, Austria. Electronic address: Christa.Noehammer@ait.ac.at.
6Medical University of Vienna, Department of Radiology, Computational Imaging Research Lab, Early Life Image Analysis (ELIA) Group, Waehringerguertel 18-20, 1090 Vienna, Austria; Medical University of Vienna, Comprehensive Center for Artificial Intelligence in Medicine, Waehringerguertel 18-20, 1090 Vienna, Austria; Christian Doppler Laboratory for Mathematical Modelling and Simulation of Next-Generation Medical Ultrasound Devices, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: roxane.licandro@meduniwien.ac.at.
7AIT Austrian Institute of Technology GmbH, Center Health & Bioresources, Competence Unit Molecular Diagnostics, Giefinggasse 4, 1210 Vienna, Austria. Electronic address: Klemens.Vierlinger@ait.ac.at.
8Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: monika.resch@kinderarztpraxis-schumanngasse.at.
9Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: angelika.berger@meduniwien.ac.at.
10Medical University of Vienna, Department of Pediatrics and Adolescent Medicine, Comprehensive Center for Pediatrics, full Member of ERN EpiCARE, Waehringerguertel 18-20, 1090 Vienna, Austria. Electronic address: katharina.goeral@meduniwien.ac.at.

Abstract

OBJECTIVE: To examine how cerebral oxygenation levels monitored by near-infrared spectroscopy (NIRS) are associated with neurodevelopmental trajectories in neonates with intraventricular hemorrhage (IVH). STUDY DESIGN: In this prospective study, 95 neonates born at <34 weeks of gestation with IVH (63 males, median gestational age: 25+6 weeks) between 2013-2023 were included. Regional cerebral oxy…

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