Peer-Reviewed Publication
Ann Surg Open2026;7(3):e705.September 1, 2026Journal Article

The Benign COMPARE Study: Comparing Perioperative Outcomes of Benign Minimally Invasive Laparoscopic, da Vinci Robotic, and Open Procedures: A Systematic Review and Meta-Analysis of Evidence.

Thomas H Shin1,2, Rocco Ricciardi3, Usha Seshadri-Kreaden4, Mansi Mathur4, Leigh A Cantrell5, Ana Yankovsky4, Kirsten Greene6, Neera M Patel4, April E Hebert4, Peter T Hallowell1
1From the Division of General Surgery, Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA.
2Division of General and Gastrointestinal Surgery, Department of Surgery, Massachusetts General Brigham, Boston, MA.
3Section of Colon and Rectal Surgery, Department of Surgery, Massachusetts General Brigham, Boston, MA.
4Biostatistics and Global Access & Evidence Management, Intuitive Surgical, Sunnyvale, CA.
5Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Virginia School of Medicine, Charlottesville, VA.
6Department of Urology, University of Virginia School of Medicine, Charlottesville, VA.

Abstract

OBJECTIVES: To assess perioperative and quality-of-life outcomes of da Vinci robotic-assisted surgery (dV-RAS), laparoscopic, and open surgery for 13 benign procedures. BACKGROUND: Prior studies demonstrate dV-RAS benefits in oncologic procedures, but potential benefits in benign procedures remain undetermined. METHODS: Preferred Reporting Items for Systematic Reviews and Meta-Analyses-guided sy…

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