Peer-Reviewed Publication
Mayo Clin Proc Digit Health2026;4(3):100375.September 1, 2026Journal Article

Real-World Body Composition and Blood Pressure Changes Following Glucagon-Like Peptide 1 Receptor Agonist Initiation: A Causal Inference Study of Connected Device Data.

Agathe Chabassier1,2,3, Benjamin Vittrant3, Pierre Binon3, Erwan Scornet1, Julie Josse2
1Sorbonne University, CNRS, Laboratory of Probability Statistics and Modelling (LPSM), Paris, France.
2Inria, Inserm, PreMeDICaL Team, University of Montpellier, France.
3Withings, Issy-les-Moulineaux, France.

Abstract

OBJECTIVE: To characterize real-world body composition and blood pressure changes following glucagon-like peptide (GLP)-1 receptor agonist (RA) initiation and identify predictors of weight loss quality using connected device data. PATIENTS AND METHODS: In this retrospective cohort study, adult US users completing an in-application GLP-1 RA survey (June 8, 2023, to July 4, 2024) were followed up u…

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