Health AI Central
Peer-Reviewed Publication
Magn Reson Med2026September 14, 2026Journal Article

Spatially Aware Acquisition-Independent Deep Learning for IVIM MRI Parameter Estimation in Patients With Esophageal Cancer.

Daan Kuppens1,2, Roman S Oort1, Sebastiano Barbieri3,4, Stella Mook5, Gert J Meijer5, Oliver J Gurney-Champion1,2
1Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center, Amsterdam, the Netherlands.
2Imaging and Biomarkers, Cancer Center Amsterdam, Amsterdam, the Netherlands.
3Queensland Digital Health Centre, University of Queensland, Brisbane, Australia.
4Centre for Big Data Research in Health, UNSW Sydney, Sydney, Australia.
5Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, the Netherlands.
PubMed DOI

Abstract

PURPOSE: Neural controlled differential equations (NCDEs) recently emerged as a robust deep learning approach for quantitative MRI parameter estimation. NCDEs offer flexibility to changes in acquisition protocols by modeling the signal evolution dynamics. However, NCDE implementations operate on a voxel-by-voxel basis and cannot exploit spatial information, limiting effectiveness. The purpose of t…

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