Health AI Central
Peer-Reviewed Publication
Eur Heart J Digit Health2026;7(8):ztag130.October 1, 2026Journal Article

Artificial intelligence-enabled electrocardiography for detection of left ventricular diastolic dysfunction: a systematic review and meta-analysis.

Johann Edjimbi1,2, Nisarg Shah3, Luca Donisi4, Aryan Gajjar5, Claudia See6, Alyssa A Grimshaw7, Hassim Bachir Diop1, Antonio Luiz P Ribeiro8,9, Eloi Marijon1,4,10, Gari Clifford11,12, Bamba Gaye1,10,12,13,14
1Alliance for Medical Research in Africa (AMedRA), Dakar, Senegal.
2Department of Medicine, Sinai Hospital of Baltimore, Maryland, USA.
3Department of Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
4Division of Cardiology, European Georges Pompidou Hospital, Paris, France.
5Department of Internal Medicine, Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
6Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
7Harvey Cushing/John Hay Whitney Medical Library, Yale University, New Haven, CT, USA.
8Department of Internal Medicine, Faculty of Medicine, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
9Telehealth Center, Hospital das Clínicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
10Paris Cardiovascular Research Center (PARCC), INSERM U970, Université Paris Cité, Paris, France.
11Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.
12Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
13Department of Preventive Medicine and Public Health, Faculty of Medicine, Pharmacy and Odontology, Cheikh Anta Diop University, Dakar, Senegal.
14Institute of Health and Development (ISED), Cheikh Anta Diop University, Dakar, Senegal.
PubMed PMC DOI PDF

Abstract

Left ventricular diastolic dysfunction (LVDD) is an early precursor to heart failure with preserved ejection fraction, and it is currently diagnosed using echocardiography, a resource-intensive and operator-dependent modality that limits large-scale screening. The 12-lead electrocardiogram (ECG) is widely available but lacks sufficient diagnostic accuracy for LVDD. Artificial intelligence (AI)-enh…

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