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Peer-Reviewed Publication
Adv Ther2026September 3, 2026Journal Article

Long-Term Cost-Effectiveness of an Advanced Hybrid Closed-Loop Automated Insulin Delivery System Versus Multiple Daily Insulin Injections Plus Continuous Glucose Monitoring in Adults with Type 1 Diabetes in Australia.

Sarah Glastras1,2, Meaghan Read3, Aslı Zeynep Ozdemir Saltik4, Marianne Huynh5, Gabrielle Challis5, Michelle Hill4, Martin Field6, Richard Pollock6, Simona de Portu4
1Kolling Institute, Faculty of Medicine and Health, University of Sydney, Sydney, NSW, Australia. sarah.glastras@sydney.edu.au.
2Department of Diabetes, Endocrinology and Metabolism, Royal North Shore Hospital, St Leonard's, Sydney, NSW, Australia. sarah.glastras@sydney.edu.au.
3Patient Author, Melbourne, VIC, Australia.
4Medtronic International Trading Sàrl, Tolochenaz, Switzerland.
5Medtronic, Macquarie Park, Sydney, NSW, Australia.
6Covalence Research Ltd, Harpenden, UK.

Abstract

INTRODUCTION: The MiniMed™ 780G (MM780G) advanced hybrid closed-loop system has been shown to help improve glycemic control compared with continuous glucose monitoring plus multiple daily injections of insulin (MDI) in people with type 1 diabetes (T1D). The long-term health economic outcomes with MM780G versus MDI + CGM in people with T1D in Australia and HbA1c levels above target were investigate…

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