Computational modelling of fibronectin-integrin interactions under electric-field stimuli.

Indrajit Tah^1,2, Abhay Nagaraj^3,4, Bikramjit Basu⁴

¹CSIR-Central Glass & Ceramic Research Institute, 196, Raja S C Mullick Road, Kolkata, 700032, India. indrajittah.cgcri@csir.res.in.

²Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.

³Indian Institute of Science Education and Research, Dr Homi Bhabha Rd, Pashan, Pune, Maharashtra 411008, India.

⁴Laboratory for Biomaterials Science and Translational Research, Materials Research Centre, Indian Institute of Science, Mathikere, Bengaluru, Karnataka 560012, India. bikram@iisc.ac.in.

PubMed DOI

Abstract

Cell-biomaterial interactions involve the adsorption of proteins on material surfaces, followed by biophysical interactions among adsorbed proteins and cell surface integrins. In a series of recent publications, it has been demonstrated that the cell fate processes can be guided by the electric field stimulations on a range of biomaterial substrates, in vitro. In efforts to understand the underlyi…

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