Association Between Changes in Serum N-Terminal Pro B-Type Natriuretic Peptide Levels and All-Cause and Cause-Specific Mortality　- The Hisayama Study.

Asahi Kato^1,2, Emi Oishi^2,3,4, Akihiro Maezono^1,2, Satoko Sakata^2,3,4, Yoshihiko Furuta^2,4, Mao Shibata^2,3,5, Jun Hata^3,6, Tetsuro Ago^3,4, Kohtaro Abe¹, Toshiharu Ninomiya^2,3

¹Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University.

²Department of Epidemiology and Public Health, Graduate School of Medical Sciences, Kyushu University.

³Center for Cohort Studies, Graduate School of Medical Sciences, Kyushu University.

⁴Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University.

⁵Department of Psychosomatic Medicine, Graduate School of Medical Sciences, Kyushu University.

⁶Department of Health Care Administration and Management, Graduate School of Medical Sciences, Kyushu University.

PubMed DOI

Abstract

BACKGROUND: Few epidemiological studies have investigated the association between changes in serum N-terminal pro B-type natriuretic peptide (NT-proBNP) and mortality in the general Asian population. METHODS AND RESULTS: We followed 2,703 community-dwelling Japanese residents aged ≥40 years who had serum NT-proBNP concentrations measured in both 2002-2003 and 2007-2008 over a median period of 10.…

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