Peer-Reviewed Publication
Neurosurg Focus2026;61(3):E18.September 1, 2026Journal Article
Diffusion MRI radiomics in meningiomas: imaging correlates of tumor grade and intraoperative consistency.
Sabino Luzzi1,2, Gianluca Lorenzo Fabozzi1,2, Salvatore Cutillo2,3, Tevfik Serhan Bora2,3, Adriana Pintus4, Sebastiano Cuccuru5, Ivana Roskova6,7, Abramo Agosti8, Lorenzo Magrassi3,9, Giuseppe Palmieri1,10,11, Antonio Cossu1,4, Mariano Scaglione1,5, Salvatore Masala1,5, Renato Galzio3
11Department of Medicine, Surgery, and Pharmacy, University of Sassari, Sardinia.
22Department of Neurosurgery, AOU Sassari, Sardinia.
33Department of Clinical-Surgical, Diagnostic and Pediatric Sciences, University of Pavia.
44Department of Pathology, AOU Sassari, Sardinia.
55Department of Radiology, AOU Sassari, Sardinia, Italy.
66Department of Neurosurgery, University Hospital Brno.
77Faculty of Medicine, Masaryk University, Brno, Czech Republic.
88Department of Mathematics, University of Pavia.
99Department of Neurosurgery, Fondazione IRCCS Policlinico San Matteo, Pavia.
1010Immuno-Oncology and Targeted Cancer Biotherapies, University of Sassari, Sardinia; and.
1111Unit of Cancer Genetics, Institute of Genetic and Biomedical Research at the National Research Council, Sassari, Sardinia, Italy.
Abstract
OBJECTIVE: Despite advancements in imaging studies, the preoperative prediction of the biological behavior and intraoperative consistency of intracranial meningiomas remains limited. This study evaluated the association of volumetric diffusion-based and texture-derived radiomic features extracted from routine MRI with histopathological aggressiveness and intraoperative tumor consistency.
METHODS:…
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